A new method for distinction between bacterial and viral infections

nujatiju submitted, created time 1 year 5 months (www.sciencedirect.com)

This landmark study describes a novel marker of local and systemic bacterial infections designated “clinical infection score (CIS) point”, which incorporates quantitative analysis of CR1 and CR3 on neutrophils and standard clinical laboratory data, CRP and ESR. CIS point varied between 0 and 8, and displayed 98% sensitivity and 97% specificity in distinguishing between bacterial and viral infections. It is well proved that the diagnostic yield of individual infection markers in distinguishing between bacterial and viral infections increases upon combination.

Keywords: Infectious diseases Differential diagnosis Neutrophils Complement receptors CR1(CD35) and CR3(C Bacterial infections Viral infections CRP ESR