Cell's Protein Recycling Systems Linked, Implications For Neurodegeneration

Dolly submitted, created time 1 year 6 months (www.medicalnewstoday.com)

Many age-related neurological diseases are associated with defective proteins accumulating in nerve cells, suggesting that the cell's normal disposal mechanisms are not operating correctly. Now, researchers at the University of Pennsylvania School of Medicine have discovered a molecular link between the cell's two major pathways for breaking down proteins and have succeeded in using this link to rescue neurodegenerative diseases in a simple animal model. The study appears this week in Nature.

Keywords: protein recycling Neurodegeneration