Chromatin fine structure of the c-MYC insulator element/DNase I-hypersensitive site I is not preserved during mitosis

davis submitted, created time 1 year 3 months (www.pnas.org)

During mitosis in higher eukaryotic cells, transcription is silenced and transcription complexes are absent from promoters in the condensed chromosomes; however, epigenetic information concerning the pattern of expressed and silent genes must be preserved.

Keywords: chromatin mitosis transcription chromosome silent gene