Coupling of Double-Stranded RNA Synthesis and siRNA Generation

jerry submitted, created time 7 months 4 days (www.sciencedirect.com)

A new study shows that heterochromatic dsRNA synthesis and siRNA generation are physically coupled processes. This coupling has implications for cis-restriction of siRNA-mediated heterochromatin assembly and for mechanisms that give rise to siRNA strand polarity.

Keywords: dsRNA double-stranded RNA siRNA RNAi RNA interference short interfering RNA