Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants.

kavin submitted, created time 7 months 2 weeks (www.ncbi.nlm.nih.gov)

Here, researchers identify the Nalp3 inflammasome as a crucial element in the adjuvant effect of aluminium adjuvants; in addition, they show that the innate inflammasome pathway can direct a humoral adaptive immune response. This is likely to affect how we design effective, safe adjuvants in the future.

Keywords: immunology adjuvants aluminum immune response Nalp3 inflammasome aluminium adjuvants immunostimulatory properties Nalp3 inflammasome