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    Drug markers questioned

    jane2007 submitted, created time 9 months 6 days (www.nature.com)

    A recent spate of worrying clinical-trial data has researchers questioning drugs approved on the basis of how they affect biomarkers rather than clinical endpoints. Heidi Ledford looks at surrogate markers.

    Keywords: high blood pressure cardiovascular disease cancer mortality biomarkers clinical trials clinical data

     
    Comments (4) Who Rated and Blogged this Blog this Email this  
    Darkfrog commented 9 months ago - Re: Drug markers questioned
    2     
    Wow. This doesn't look as flashy as the hybrid embryo article, but this is our whole system of drug approval under review.
    davidd commented 9 months ago - Re: Drug markers questioned
    1     
    The surrogate markers plays a significant role in drug approval, and has some shortcomings. But the problem is very difficult to solve. The patient should get a choice to choose a drug to save their lives.
    jane2007 commented 9 months ago - Re: Drug markers questioned
    1     
    This article told us many problems on drug research, drug development,and drug regulate.FDA is remiss, they should improve effect and be responsible for the safey of drug before they are on sales.
    Sue Wu commented 9 months ago - Re: Drug markers questioned
    2     
    People neglect the long-time side-effcts in using the drugs. I believe that this is not the first time we take actions after limited judgement in curing diseases. Not a single judgement is perfect right, but we can manage to conquer the shortcomings.
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