How the regulatory protein, IF1, inhibits F1-ATPase from bovine mitochondria

william submitted, created time 1 year 1 month (www.pnas.org)

The structure of bovine F1-ATPase inhibited by a monomeric form of the inhibitor protein, IF1, known as I1–60His, lacking most of the dimerization region, has been determined at 2.1-Å resolution. The resolved region of the inhibitor from residues 8–50 consists of an extended structure from residues 8–13, followed by two -helices from residues 14–18 and residues 21–50 linked by a turn.

Keywords: regulatory protein mitochondria