The mechanics of translocation

jerry submitted, created time 5 months 2 weeks (www.sciencedirect.com)

Stepwise addition of amino acids to the growing polypeptide chain requires the coordinated movement of mRNA and tRNAs through the ribosome, a process known as translocation. Researchers review current understanding of the kinetics and mechanics of translocation, with emphasis on the structure of a functional mammalian ribosome stalled during translocation by an mRNA pseudoknot.

Keywords: tRNA mRNA molecular biology polypeptides translocation