Articles with the keyword: 
Increased Mortality after Dronedarone Therapy for Severe Heart Failure
kavin submitted, created time 2 years 2 months (content.nejm.org)
Background: Dronedarone is a novel antiarrhythmic drug with electrophysiological properties that are similar to those of amiodarone, but it does not contain iodine and thus does not cause iodine-related adverse reactions. Therefore, it may be of value in the treatment of patients with heart failure.
Methods: In a multicenter study with a double-blind design, we planned to randomly assign 1000 patients who were hospitalized with symptomatic heart failure and severe left ventricular systolic dysfunction to receive 400 mg of dronedarone twice a day or placebo 
Treating chronic pain without side-effects?
Sue Wu submitted, created time 2 years 7 months (www.nature.com)
A drug has been found that treats chronic pain in mice, without the usual painkiller side effects of sedation, addiction or developing tolerance.
Building a New Heart From Old Tissue
Eric wu submitted, created time 2 years 7 months (sciencenow.sciencemag.org)
Approximately 3000 patients in the United States are on the waiting list for a heart transplant, but only about 2000 donor organs become available each year.
This article put forward a new method to solve the life-and-death problem.It includes two pivotal factors:The first one is that we need to find an appropriate stem cell that can give rise to heart tissue;The second one is that the cells require a framework, or scaffolding, to grow on.
Do you think it is feasible to resolve the difficult medical problem?
Trimetazidine improves endothelial dysfunction in chronic heart failure: an antioxidant effect
amanda submitted, created time 3 years 3 months (eurheartj.oxfordjournals.org)
"TMZ improves the ED-relaxation in patients with ischaemic cardiomyopathy. The antioxidant properties of TMZ may play a role. "
badboy submitted, created time 3 years 4 months (eurheartj.oxfordjournals.org)
" S-SMase is upregulated in CHF, independent of aetiology. The association of S-SMase with clinical status, tissue amount, functional capacity of skeletal muscle tissue, and vasodilator capacity suggests that S-SMase-mediated signalling may contribute to regulatory processes of CHF pathophysiology. "
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