Articles with the keyword: 


Higher coffee consumption associated with lower liver cancer risk
kavin submitted, created time 6 months 1 week (esciencenews.com)
A new large, prospective population-based study confirms an inverse relationship between coffee consumption and liver cancer risk. The study also found that higher levels of gamma-glutamyltransferase (GGT) in the blood were associated with an increased risk of developing the disease. These findings are published in the July issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article and an accompanying editorial are also available online at Wiley Interscience (www.interscience.wiley.com) 


Genetic Variation Doubles Risk of Liver Cancer
Sue Wu submitted, created time 1 year 5 days (health.usnews.com)
WEDNESDAY, Jan. 2 (HealthDay News) -- A single change in the epidermal growth factor (EFG) gene may double the risk of developing liver tumors, especially among people with cirrhosis, new research suggests. 


New treatment option studied for bladder cancer
MedColGa submitted, created time 1 year 2 months (www.discover8.com)
A chemotherapy regimen for patients with advanced bladder cancer who aren’t eligible for standard treatment is under study at the Medical College of Georgia. 


Advance In The Search For An Effective Treatment For Liver Cancer
cappuccion submitted, created time 1 year 5 months (www.medicalnewstoday.com)
Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics. Using a newly available monoclonal antibody, they demonstrated significant reductions in tumor cell proliferation and survival in human and mouse hepatocellular cancer (HCC) cell lines. According to the researchers, this finding has significant implications not only for the treatment of liver cancer but for a number of different types of cancer. 


Antibody retards liver cancer cell growth
bianjie submitted, created time 1 year 5 months (www.sciencedaily.com)
U.S. oncologists have used a new monoclonal antibody to achieve significant reductions in liver cancer tumor growth in both human and mouse models. 


Antibody retards growth and induces death in liver cancer cells
bianjie submitted, created time 1 year 5 months (www.eurekalert.org)
Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer. Using a newly available monoclonal antibody, they demonstrated dramatic reductions in tumor cell proliferation and survival in human and mouse hepatocellular cancer cell lines. This finding has significant implications not only for the treatment of liver cancer but for a number of different types of cancer. 


Why liver cancer is more prevalent in males than in females
bianjie submitted, created time 1 year 6 months (www.eurekalert.org)
Production of a protein that promotes inflammation appears to be linked to the higher incidence of liver cancer in men than in women, researchers at the University of California, San Diego School of Medicine have determined in mouse studies. 


Computed tomography as liver cancer mRNA profiling proxy
red monkey submitted, created time 1 year 6 months (www.nature.com)
"Paralleling the diversity of genetic and protein activities, pathologic human tissues also exhibit diverse radiographic features. Here we show that dynamic imaging traits in non-invasive computed tomography (CT) systematically correlate with the global gene expression programs of primary human liver cancer. Combinations of twenty-eight imaging traits can reconstruct 78% of the global gene expression profiles, revealing cell proliferation, liver synthetic function, and patient prognosis 


Nexavar significantly extends overall survival by 44 percent in liver cancer patients
broadcast submitted, created time 1 year 7 months (www.eurekalert.org)
Bayer HealthCare Pharmaceuticals Inc. (NYSE: BAY) and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that Nexavar� (sorafenib) tablets significantly extended overall survival in patients with hepatocellular carcinoma (HCC), or primary liver cancer versus those taking placebo by 44% (HR=0.69; p-value=0.0006). Results were presented at the 43rd annual meeting of the American Society of Clinical Oncology (ASCO). 


Study: Nexavar Extends Survival In Liver Cancer Patients
DanyC submitted, created time 1 year 7 months (money.cnn.com)
A study of 602 patients showed those receiving Nexavar had a median overall survival of 10.7 months compared to 7.9 months among patients taking placebo. About half the patients received Nexavar while the other half received placebo, or a fake treatment. Patients in the study had advanced liver cancer that could not be cured by surgery. Researchers said the survival difference translates into a significant 44% survival advantage for patients in the Nexavar group compared to those in the placebo group. 


Study: Liver Cancer Breakthrough Found
deirdre submitted, created time 1 year 7 months (www.examiner.com)
For the first time, doctors say they have found a pill that improves survival in liver cancer, a notoriously hard to treat disease diagnosed in more than half a million people globally each year. 


badboy submitted, created time 1 year 7 months (jama.ama-assn.org)
"Hepatitis C virus infection confers a 20% to 30% increased risk of non-Hodgkin lymphoma overall, and a 3-fold higher risk of Waldenström macroglobulinemia, a low-grade lymphoma. Risks were also increased for cryoglobulinemia. These results support an etiological role for HCV in causing lymphoproliferation and causing non-Hodgkin lymphoma. " 


Mailman School of Public Health researchers report blood DNA can be early predictor of liver cancer
alpha submitted, created time 1 year 8 months (www.biologynews.net)
"Researchers at Columbia University’s Mailman School of Public Health have discovered a means for early detection of liver cancer. Using DNA isolated from serum samples as a baseline biomarker, the scientists examined changes in certain tumor suppressor genes that have been associated with the development of liver carcinomas. This is the first study to prospectively examine potential biomarkers for early detection of liver cancer in high-risk populations, including those with chronic hepatitis B and C virus infections." 


nflammatory Tales of Liver Cancer
biscuits submitted, created time 1 year 10 months (www.cancercell.org)
Cell culture studies have established NF-κB's critical role in cancer cell survival and proliferation and led to the clinical use of NF-κB inhibitors. However, a paper in this issue of Cancer Cell reveals an anticancer function for NF-κB in a mouse model where NF-κB activity is lost specifically in hepatocytes. These studies suggest careful examination of NF-κB inhibitors as a therapeutic modality for cancer. 
\ 1
\