MOF is a Key Regulator of Dosage Compensation and Gene Expression in Drosophila

kavin submitted, created time 7 months 6 days (www.cell.com)

Here the researchers report that the histone H4 lysine 16 (H4K16) specific histone acetyltransferase MOF displays differential binding behavior depending on whether the target gene is located on the X chromosome versus the autosomes. In conclusion, MOF is not only involved in the onset of dosage compensation, but also acts as a regulator of gene expression in the Drosophila genome.

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