Vaccine Injury Case Offers a Clue to the Causes of Autism

jane2007 submitted, created time 8 months 2 weeks (www.sciam.com)

Could a group of disorders involving the power plants of the cell explain why some vaccinated children develop autism but the vast majority don't?

1 comment | Blog It | Email It | Keywords: autism mitochondrial dysfunction mitochondria childhood vaccines vaccines and autism mitochondrial disorders vaccines

Mitochondrial Dysfunction Accounts for the Stochastic Heterogeneity in Telomere-Dependent Senescence

deirdre submitted, created time 1 year 8 months (biology.plosjournals.org)

"Senescence, which is triggered by the loss of DNA sequences at the ends of chromosomes (telomeres), is often seen as an example of a regular “biological clock.” However, cell senescence is heterogeneous, with large differences in lifespan between individual cell lineages. We found that mitochondrial function deteriorated while cells approached senescence, leading to increased ROS production. Delaying mitochondrial dysfunction led to postponed replicative senescence and slowing of telomere shortening

Submit comment | Blog It | Email It | Keywords: Mitochondrial Dysfunction reactive oxygen species (ROS) heterogeneity