A better understanding of inherited breast cancer

sea-maid submitted, created time 2 months 1 week (www.sciencenews.org)

One of the molecular players in breast cancer arising from an inherited mutation has a surprising role in squelching tumors.

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Chinese medicine gets a ne w change

Paradise submitted, created time 1 year 4 months (www.reutershealth.com)

Con trast to traditional Chinese medicine, the ancient art of healing using natural ingredients that are often boiled or powdered, is getting a modern dose.

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Sickle cell disease: old discoveries, new concepts, and future promise

medal submitted, created time 1 year 8 months (www.jci.org)

"The discovery of the molecular basis of sickle cell disease was an important landmark in molecular medicine. The modern tools of molecular and cellular biology have refined our understanding of its pathophysiology and facilitated the development of new therapies. In this review, we discuss some of the important advances in this field and the impediments that limit the impact of these advances. "

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Evolution of protein complexes by duplication of homomeric interactions

angelfish submitted, created time 1 year 9 months (genomebiology.com)

"Researchers study protein complexes in Saccharomyces cerevisiae, complexes of known three-dimensional structure in the Protein Data Bank and clusters of pairwise protein interactions in the networks of several organisms. They find that duplication of homomeric interactions, a large class of protein interactions, frequently results in the formation of complexes of paralogous proteins. This route is a common mechanism for the evolution of complexes and clusters of protein interactions. Their conclusions are further confirmed by theoretical modelling of network evolution

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