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8

Mutation Spells Bad News for Breast Cancer Patients

sea-maid submitted, created time 5 months 3 weeks (sciencenow.sciencemag.org)

Breast cancer patients with a mutation in both copies of the NQO1 gene have a 20% lower survival rate five years after treatment than do patients without the mutation, according to a new study of more than 2000 Finnish women.

5

Substance In Tree Bark Could Lead To New Lung-cancer Treatment

gh0706 submitted, created time 1 year 4 months (www.sciencedaily.com)

Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer. In the new study, the researchers found that beta-lapachone interacts with an enzyme called NQO1, which is present at high levels in non-small cell lung cancer and other solid tumors

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