Articles with the keyword: 
Common Oral Osteoporosis Drugs Linked to Serious Jaw Necrosis
sea-maid submitted, created time 4 days 7 hours (www.sciencedaily.com)
Researchers at the University Of Southern California, School Of Dentistry release results of clinical data that links oral bisphosphonates to increased jaw necrosis. The study is among the first to acknowledge that even short-term use of common oral osteoporosis drugs may leave the jaw vulnerable to devastating necrosis, according to a new report. 
New Osteoporosis Drugs in the Works
jerry submitted, created time 3 months 2 weeks (www.webmd.com)
Two experimental osteoporosis drugs are getting attention from bone experts -- and may become the first biologic drugs to treat osteoporosis. Both these drugs work by targeting osteoclasts--the cells that break down bone--giving their bone-building counterparts, called osteoblasts, time to catch up.
Hormone injections can strengthen bones
sumsung submitted, created time 9 months 4 weeks (www.nature.com)
Weekly or semiweekly injections of a hormone that stimulates the thyroid gland can also strengthen bones in rodents, researchers have found. The hormone, called thyroid-stimulating hormone (TSH), is already available as a therapy for thyroid cancer patients, and clinical studies are now under way to determine whether it might also be used to fight the debilitating bone-wasting disease osteoporosis.
sumsung submitted, created time 10 months 4 days (sciencenow.sciencemag.org)
Researchers have unearthed new clues behind a disease that effectively turns young children into senior citizens. A protein called progerin prods stem cells to go astray, causing them to mature into the wrong cell types. The findings may have implications for understanding normal aging as well.
Notch controls bone formation and strength
jane2007 submitted, created time 10 months 1 week (www.bcm.edu)
Notch, a protein known to govern the determination of cell differentiation into different kinds of tissues in embryos, plays a critical role in bone formation and strength later in life. These findings may provide a basis for understanding osteoporosis and diseases in which there is too much bone.
Extra calcium may raise health risks in older women
Sue Wu submitted, created time 11 months 3 weeks (www.reuters.com)
"Calcium supplements are commonly prescribed to postmenopausal women to maintain bone health, and some data suggest it might protect against vascular disease by lowering levels of LDL cholesterol, the so-called 'bad cholesterol', in the blood."
Denosumab fortifies bone in breast cancer patients
Eric wu submitted, created time 1 year 3 weeks (www.reuters.com)
The osteoporosis drug denosumab increased bone strength in women receiving hormone therapy for breast cancer, drug maker Amgen Inc said Friday.
Diabetes Drug Linked to Osteoporosis
Eric wu submitted, created time 1 year 1 month (www.time.com)
The popular diabetes drug marketed as Avandia may increase bone thinning, a discovery that could help explain why diabetics can have an increased risk of fractures.
Study shows some athletic men may risk low bone density
sumsung submitted, created time 1 year 2 months (munews.missouri.edu)
According to the National Osteoporosis Foundation, osteoporosis affects more than 2 million men in the United States and nearly 12 million more have osteopenia -- clinically significant low bone density that is less severe than osteoporosis. Now, a new study from the University of Missouri-Columbia has found that men engaging predominantly in low-impact forms of exercise have an increased incidence of osteopenia -- a condition resulting in two times the risk of bone fracture.
red monkey submitted, created time 1 year 6 months (www.nature.com)
Parathyroid hormone peptides are an exciting new therapeutic option for patients with osteoporosis. In this Practice Point Commentary, Dr Compston discusses the recent findings of the meta-analysis by Vestergaard et al., highlighting the issues related to the use of parathyroid hormone treatment in clinical practice. Topics of discussion include the effect of parathyroid hormone peptides on risk of hip fracture, the optimal duration of treatment, and the role of combination therapy with anti-resorptive agents.
Women Up to Age 30 at Risk for Bone Loss, Study Finds
bioman submitted, created time 1 year 7 months (news.research.ohiou.edu)
Rigorous exercise and extreme dieting can predispose females to osteoporosis. Women who follow strict exercise and diet regimens may harm their body’s ability to form new bone, which can lead to osteoporosis later in life. Researchers recommend that the more women exercise, the more they need to eat to stay healthy.
Once-a-year Drug Reduces Fractures From Osteoporosis
dovechocolate submitted, created time 1 year 8 months (www.sciencedaily.com)
A treatment for osteoporosis delivered once a year is as effective as current monthly or weekly osteoporosis regimens at reducing the incidence of bone fractures, according to a new study led by a UCSF research team.
addict submitted, created time 1 year 8 months (www.pnas.org)
Once-daily s.c. administration of either human parathyroid hormone (PTH)-(1-84) or recombinant human PTH-(1-34) provides for dramatic increases in bone mass in women with postmenopausal osteoporosis. They initiated a program to discover orally bioavailable small molecule equivalents of these peptides. Their experiment these experiments indicated that the highly modified 14 amino acid peptide induces qualitatively similar biological responses to those produced by PTH-(1-34), albeit with lower potency relative to the parent peptide
fiona submitted, created time 1 year 9 months (www.annals.org)
"Bone loss that occurred with ADT was prevented and improved with once-weekly oral alendronate. Because most men have low bone mass or osteoporosis, physicians should assess their patients' bone density and provide preventive and therapeutic measures as appropriate. "
Bone Mineral Density and its Related Factors in Elderly Male Chinese Patients with Type 2 Diabetes
biscuits submitted, created time 1 year 10 months (www.arcmedres.com)
There have been few investigations conducted on the epidemiology and risk factors of osteoporosis in patients with diabetes in China. The aim of this study was to disclose the percentage and the possible risk factors that influence bone mineral density (BMD) in this population.
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