Genetic interaction with smoking in arthritis

jerry submitted, created time 8 months 15 hours (arthritis-research.com)

Analysis of data from a study of American nurses confirms the PTPN22 polymorphism is a strong risk factor for rheumatoid arthritis, and that its presence interacts multiplicatively with heavy smoking.

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Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population

diefish submitted, created time 1 year 4 months (www.biomedcentral.com)

“Researchers' results provide evidence that the PTPN22 1858T allele is a T1D susceptibility factor also in the Spanish population and it might play a different role in susceptibility to T1D according to gender in early-onset T1D patients.”

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