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Cochlear Amplifier Is Silenced by Immobilizing Prestin

jerry submitted, created time 7 months 3 weeks (www.neuron.org)

Achieving the exquisite sensitivity and frequency selectivity of the mammalian ear requires active amplification of input sound.

This article demonstrates that the molecular motor prestin, which drives shape changes in the soma of mechanosensory hair cells, underlies mechanical feedback mechanisms for sound amplification in mammals.

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