Human osteosarcoma cells express NF-kappa B

BIOBOSS submitted, created time 1 year 10 months (www3.interscience.wiley.com)

This study is the first report of functional RANK expression in human osteosarcoma cells: this strengthens the involvement of the RANK-RANKL-OPG axis in primary bone tumour biology and identifies novel therapeutic approaches targeting RANK-positive osteosarcoma.

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