Structure and Stability of DNA Watson-Crick Base Pairs and Effects of the Molecular Environment

DNA co-discoverer Watson gets his genome sequenced

captainclaw submitted, created time 1 year 7 months (www.reutershealth.com)

More than 50 years after helping to uncover the double-helix structure of DNA, James D. Watson has seen his own genome, and said on Thursday he will publish it for science to use.

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A Left-Handed RNA Double Helix Bound by the Zα Domain of the RNA-Editing Enzyme ADAR1

addict submitted, created time 1 year 8 months (www.structure.org)

The A form RNA double helix can be transformed to a left-handed helix, called Z-RNA. Currently, little is known about the detailed structural features of Z-RNA or its involvement in cellular processes. Here, they present the 2.25 Å crystal structure of the Zα domain of the RNA-editing enzyme ADAR1 (double-stranded RNA adenosine deaminase) complexed to a dUr(CG)3 duplex RNA. The Z-RNA helix is associated with a unique solvent pattern that distinguishes it from the otherwise similar conformation of Z-DNA

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