Hydrogen Bonds of RNA Are Stronger than Those of DNA, but NMR Monitors Only Presence of Methyl Substituent in Uracil/Thymine, not Bond Strength

Novel drug discovery and molecular biological methods, via DNA, RNA and protein changes using structure–function transitions: Transitional structural chemogenomics, transitional structural nucleic acid microarray

DNAMENYIT submitted, created time 1 year 4 months (iris.nyit.edu)

Nucleic acids and proteins are dynamic molecules that undergo structural changes which control gene expression. The authors have developed two novel techniques, viz., transitional structural chemogenomics and
transitional structural chemoproteomics. Transitional structural chemogenomics is used to regulate gene expression, employing ultrasensitive small-molecule drugs targeted toward nucleic acids. Gene expression can be regulated by
using chemicals to target transitional changes in the helical conformations of single-stranded (ss-) and double-stranded (ds-) DNA (e.g

4 comments | Blog It | Email It | Keywords: RNA, DNA,GENE single-stranded DNA gene expression microarrays RNA-DNA hybrid stability gene expression microarray Nuclear Gene Expression gene expression profile RNA, DNA,GENE Single-Stranded DNA gene expression microarrays RNA-DNA hybrid stability gene expression microarray Nuclear Gene Expression gene expression profile

Mitochondrial DNA analysis of field populations of Helicoverpa armigera (Lepidoptera:Noctuidae) and of its relationship to H. zea

DanyC submitted, created time 1 year 5 months (www.biomedcentral.com)

"This mitochondrial DNA sequence data supports the single species status of H. armigera across Africa, Asia and Australia. The evidence for inter-continental gene flow observed in this study is consistent with published evidence of the capacity of this species to migrate over long distances. The finding of high genetic similarity between Old World H. armigera and New World H. zea emphasises the need to consider work on both pests when building pest management strategies for either."

Submit comment | Blog It | Email It | Keywords: RNA, DNA,GENE genomic DNA

New RNA Muddies Gene Definition

Cassidy submitted, created time 1 year 7 months (www.sciam.com)

A scientific team has identified three new classes of RNA, along with evidence that genes become more active as these strange RNA molecules become shorter. So this make us doubt the original gene definition.

Submit comment | Blog It | Email It | Keywords: RNA, DNA,GENE