jerry submitted, created time 6 months 3 weeks (stke.sciencemag.org)

GTPases have long been known to control the activities of downstream protein kinases. Now this paper shows that the kinase activity of one of these ROCO proteins depends on whether guanosine diphosphate or guanosine triphosphate (GTP) is bound and that the activity is controlled by the adjacent GTPase, which suggests a novel mechanism of intrinsic control.

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