Articles with the keyword:
11

Rosiglitazone-Associated Fractures in Type 2 Diabetes

jerry submitted, created time 6 months 1 week (care.diabetesjournals.org)

This is an analysis from a diabetes outcome progression trial.
It said that further investigation into the risk factors and underlying pathophysiology for the increased fracture rate in women taking rosiglitazone is required to relate them to preclinical data and better understand the clinical implications of and possible interventions for these findings

5

Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

cappuccion submitted, created time 1 year 5 months (content.nejm.org)

Rosiglitazone is widely used to treat patients with type 2 diabetes mellitus, but its effect on cardiovascular morbidity and mortality has not been determined. We conducted searches of the published literature, the Web site of the Food and Drug Administration, and a clinical-trials registry maintained by the drug manufacturer (GlaxoSmithKline). Rosiglitazone was associated with a significant increase in the risk of myocardial infarction and with an increase in the risk of death from cardiovascular causes that had borderline significance

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