Antibody fights AIDS-like disease in monkeys

sea-maid submitted, created time 3 weeks 5 days (www.nature.com)

An antibody treatment has rejuvenated the immune systems of macaques infected with a virus called SIV, allowing the monkeys to fend off the symptoms of an AIDS-like disease for months. SIV is studied as a model for HIV infection in humans, and the therapy could be tested in clinical trials of HIV-infected patients as soon as next year, pending approval by regulators.

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Effects of simian immunodeficiency virus on the circadian rhythms of body temperature and gross locomotor activity

zibba submitted, created time 1 year 3 months (www.pnas.org)

In monkeys infected with simian immunodeficiency virus (SIV), changes in body temperature and locomotor activity occur after the acute retroviral syndrome stage of the disease. However, alterations to the circadian rhythm of these factors in SIV-infected monkeys have not been reported.

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Adaptation of a Diverse Simian Immunodeficiency Virus Population to a New Host Is Revealed through a Systematic Approach to Identify Amino Acid Sites under Selection

medal submitted, created time 1 year 9 months (mbe.oxfordjournals.org)

"Simian immunodeficiency viruses (SIV) have had considerable success at crossing species barriers; both human immunodeficiency virus (HIV)-1 and HIV-2 have been transmitted on multiple occasions from SIV-infected natural host species."

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