Two New Compounds Show Promise for Eliminating Breast Cancer Tumors

piggy submitted, created time 1 month 2 weeks (www.sciencedaily.com)

Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors. The compounds disrupt bonding of a cancer-related protein.

Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up a cancer-causing protein called STAT3, and researchers have observed no negative side effects so far.

"The compounds are very promising," Turkson said

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Physiologically Achievable Concentrations of Genistein Enhance Telomerase Activity in Prostate Cancer Cells via the Activation of STAT3

jiangyun submitted, created time 1 year 4 months (carcin.oxfordjournals.org)

Although it is generally known that the phytoestrogen, genistein, has telomerase-repressing and anti-proliferative effects on various cancer cells at pharmacological concentrations, we report here that physiologically achievable concentrations of genistein enhance telomerase activity, the proliferation of human prostate cancer cells, and tumor growth in the Transgenic Adenocarcinoma Mouse Prostate (TRAMP) model.

Submit comment | Blog It | Email It | Keywords: Genistein Prostate cancer STAT3 Telomerase TERT TRAMP