The emergence of Stenotrophomonas maltophilia ...exaggerated

sea-maid submitted, created time 6 months 3 weeks (www.bmj.com)

Headlines about S maltophilia, including "no antibiotics can stop it" and "rising death toll in hospitals" are unfounded, write Georgia Duckworth and Alan Johnson, from the Health Protection Agency's Centre for Infections in London. In fact, they say, S maltophilia infections are relatively rare compared to infections caused by bacteria such as meticillin resistant Staphylococcus aureus (MRSA).

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Persistent Staphylococcus aureus Bacteremia

wugongliang submitted, created time 1 year 3 months (www.discover8.com)

"This retrospective case-control study compares the clinical characteristics, management, and outcomes of 84 patients with persistent Staphylococcus aureus bacteremia (pSAB) (> 7 days of bacteremia) and 152 patients with nonpersistent S aureus bacteremia (< 3 days of bacteremia). Methicillin resistance, intravascular catheter or other foreign body use, chronic renal failure, more than 2 sites of infection, and infective endocarditis were all independently associated with pSAB. The mean time to device removal was also significantly longer among patients with pSAB

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How staphylococcus aureus evade IgA immunity

davidd submitted, created time 1 year 3 months (www.pnas.org)

Staphylococcal superantigen-like protein SSL7, potently binds IgA and C5, thereby inhibiting immune responses dependent on these major immune mediators. They report there the three-dimensional structure of the complex of SSL7 with Fc of human IgA1 at 3.2 Å resolution.

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Staphylococcus aureus lies low in cells

Rhett submitted, created time 1 year 5 months (www.biomedcentral.com)

Intracellular survival of S. aureus is aided by changes in bacterial gene expression, which include the suppression of metabolic genes and host-directed toxins, ultimately allowing the pathogen to evade antibiotics and immune defenses.

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Fusidic acid-resistant Staphylococcus aureus (FRSA) carriage in patients with atopic eczema and pattern of prior topical fusidic acid use

gh0706 submitted, created time 1 year 6 months (www.sciencedirect.com)

The researchers questioned 62 dermatology outpatients with atopic eczema and Staphylococcus aureus colonisation regarding their use of topical preparations containing fusidic acid during the previous 6 months as well as the pattern of any such use. Recent exposure to topical fusidic acid was significantly correlated with the presence of fusidic acid-resistant S. aureus (FRSA) (P = 0.04). There was also a significant trend towards increasing FRSA carriage with increased duration of use

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