Articles with the keyword:
14

Stem Cells with Potential to Regenerate Injured Liver Tissue Identified

sea-maid submitted, created time 1 day 15 hours (www.sciencedaily.com)

A novel protein marker has been found that identifies rare adult liver stem cells, whose ability to regenerate injured liver tissue has the potential for cell-replacement therapy. For the first time, researchers at the University of Pennsylvania School of Medicine led by Linda Greenbaum, MD, Assistant Professor of Medicine in the Division of Gastroenterology, have demonstrated that cells expressing the marker can differentiate into both liver cells and cells that line the bile duct.

This discovery could have serious implication for transplants and regenerative medicine

9

Genzyme and Osiris partner on stem-cell program

piggy submitted, created time 1 week 6 days (www.boston.com)

Genzyme Corp. and Osiris Therapeutics Inc. said today they will partner to develop and commercialize adult stem cell products with the potential to treat a variety of diseases.

In a press release describing the agreement, Genzyme of Cambridge said it will make a $130 million up-front payment to Maryland-based Osiris, with $75 million paid initially and $55 million to be paid on July 1, 2009. In addition, Osiris also has the potential to receive a total of up to $1.25 billion in milestone payments from Genzyme

10

MAPC adult stem cells shown to be a hoax ...or at least an error

sea-maid submitted, created time 1 month 5 days (www.newscientist.com)

This is a simple and concise writeup of the recent scandal involving stem cell research team led by Catherine Verfaille of the University of Minnesota that is accused of falsifying data. As it turns out, some of the inconsistencies in the paper in question were only errors, but it has been confirmed that there was also misrepresentation involved. For example, two of the images accompanying a paper that the team published in the journal Blood, meant to represent the results of different experiments, were actually the same image, flipped and altered

8

Stem cells from testicles offer an alternative to embryos

jerry submitted, created time 1 month 1 week (ap.google.com)

Cells taken from men's testicles seem as versatile as the stem cells derived from embryos, researchers reported Wednesday in what may be yet another new approach in a burgeoning scientific field. The downside? Because of their source, these cells could only be used for regenerative medicine in male patients, not in female ones.

The study involved twenty-two samples from men aged seventeen to eighty-one. All of them men were undergoing treatments for other reasons

7

DNA "Tattoos" Link Adult, Daughter Stem Cells in Planarians

sea-maid submitted, created time 2 months 3 days (www.sciencedaily.com)

The title of this article is poetic, but it could stand to be better organized. The authors refer to a certain method of DNA identification as a "tattoo," but don't immediately say what it is. One has to dig through the repetitive and error-strewn paragraphs before one finds this:

"the researchers devised methods to detect specific differences in gene expression in the BrdU-labeled cells. The researchers identified 259 genes associated with the stem cells and their daughters

8

Can you turn teeth into sperm?

sea-maid submitted, created time 4 months 2 days (www.newscientist.com)

COULD sacrificing a tooth enable some infertile men to father children? That's the goal of researchers in Brazil, who suggest that stem cells from human teeth can be coaxed into becoming sperm by being injected into the testes of mice.

Irina Kerkis of the Butantan Institute in São Paulo and her colleagues injected stem cells from the dental pulp of human teeth into the testes of live mice. The cells seemed to migrate to the tubules where sperm usually mature and differentiate into cells resembling human sperm

11

Stem cell treatment leaves boy with recessive epidermolysis bullosa improving daily

Darkfrog submitted, created time 5 months 1 week (www.latimes.com)

Two-year-old Nate Liao is eating solid food, playing with his sibs and generally running around and getting into things. The reason? His body has started producing collagen VII, the material that anchor's a person's skin to the rest of his body. Before he was treated, the least contact could cause bruising and blisters. Eating anything non-liquid could tear the lining of his esophagus.

Some of Nate's doctors are suggesting that epidermolysis bullosa be taken "off the incurable list." Little Nate was given a mixture of bone marrow and cord blood stem cells

6

Injured vets may regrow body parts

jerry submitted, created time 5 months 3 weeks (edition.cnn.com)

The news shows salamander-inspired therapy may aid injured vets. A wounded American soldier underwent a history-making procedure that could help him regrow the finger that was lost to a bomb attack in Baghdad last year...

8

Scientists create artificial sperm cells

Eric wu submitted, created time 9 months 2 weeks (blogs.usatoday.com)

A breakthrough news I have seen on Tencent.com in China. Here is the English version I have found on internet.

7

Building a New Heart From Old Tissue

Eric wu submitted, created time 10 months 4 days (sciencenow.sciencemag.org)

Approximately 3000 patients in the United States are on the waiting list for a heart transplant, but only about 2000 donor organs become available each year.

This article put forward a new method to solve the life-and-death problem.It includes two pivotal factors:The first one is that we need to find an appropriate stem cell that can give rise to heart tissue;The second one is that the cells require a framework, or scaffolding, to grow on.

Do you think it is feasible to resolve the difficult medical problem?

6

Good News: Stem Cells Overpower Muscle Disease

Eric wu submitted, created time 11 months 5 days (sciencenow.sciencemag.org)

The recent breakthrough of skin cells reprogrammed to behave like embryonic stem cells has stolen the spotlight (ScienceNOW, 6 December), but adult stem cells are proving that they have advantages of their own. In the 13 December issue of Cell Stem Cell, researchers report using stem cells from patients afflicted with a form of muscular dystrophy to correct the disorder in mice. The results suggest that this strategy could one day treat muscular dystrophy in humans as well as other genetic disorders.

5

New Jersey votes on $450 million for stem cell research -- can we afford it?

Darkfrog submitted, created time 1 year 1 week (www.nytimes.com)

Today is election day in my beloved homeland. Today we have a referendum on a $450 million bond for stem cell research, $45 million per year for ten years. (For my non-US buds out there, that means that the citizens all vote "yes" or "no" directly, instead of leaving it up to the elected state legislature.) The direct wording only says "stem cell research projects," but it is meant to cover adult, fetal, amniotic, embryonic and other stem cell projects, human and otherwise

8

Researcher Identifies Stem Cells In Tendons That Regenerate Tissue

june submitted, created time 1 year 2 months (www.medicalnewstoday.com)

Athletes know that damage to a tendon can signal an end to their professional careers. But a consortium of scientists, led in part by USC School of Dentistry researcher Songtao Shi, has identified unique cells within the adult tendon that have stem-cell characteristics including the ability to proliferate and self-renew. The research team was able to isolate these cells and regenerate tendon like tissue in the animal model. Their findings hold tremendous promise for the treatment of tendon injuries caused by overuse and trauma.

10

Study Shows Novel Way to Trigger New Neuron Production in the Aging Brain

akshetty2007 submitted, created time 1 year 2 months (www.dukehealth.org)

DURHAM, N.C. -- Researchers have shown for the first time that putting two specific types of neural cells directly into an aging brain can kick-start creation of brain cells linked to learning and memory.

It has been shown over the last decade that brain cells replicate, a finding that had run counter to previously accepted dogma. The area where neuron-forming stem cells perform much of this replication is the hippocampus, part of the brain linked to memory and learning, and an area affected in older people as well as those with Alzheimer's disease

5

Can Adult Stem Cells Do It All?

freeman submitted, created time 1 year 4 months (www.sciam.com)

Stem cells have been hailed by scientists as the great hope to one day prevent, halt and even reverse damage from diabetes, spinal cord injuries and degenerative diseases. But researchers complain that political roadblocks are keeping them from determining the full potential of these cells.

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