Articles with the keyword:
1

Doctors say marrow transplant may have cured AIDS

sea-maid submitted, created time 1 day 23 hours (health.yahoo.com)

An American man who suffered from AIDS appears to have been cured of the disease twenty months after receiving a targeted bone marrow transplant normally used to fight leukemia, his doctors said.

While researchers--and the doctors themselves--caution that the case might be no more than a fluke, others say it may inspire a greater interest in gene therapy to fight the disease that claims 2 million lives each year. The virus has infected 33 million people worldwide.

Dr

8

Bone marrow transplant suppresses AIDS in patient

sea-maid submitted, created time 1 week 3 days (www.reuters.com)

A bone marrow transplant using stem cells from a donor with natural genetic resistance to the AIDS virus has left an HIV patient free of infection for nearly two years, German researchers.

The patient, an American living in Berlin, was infected with the human immunodeficiency virus that causes AIDS and also had leukemia. The best treatment for the leukemia was a bone marrow transplant, which takes the stem cells from a healthy donor's immune system to replace the patient's cancer-ridden cells.

Dr

11

HIV vaccine failure explained?

sea-maid submitted, created time 2 weeks 3 days (www.nature.com)

Researchers have suggested that an experimental vaccine against AIDS might have failed in part because it made some people's immune cells more vulnerable to HIV infection.

10

Earlier HIV treatment can save more lives

sea-maid submitted, created time 3 weeks 1 day (www.sciencenews.org)

Treating HIV earlier can increase a patient’s survival chances, a new study of more than 8,000 HIV patients shows. The findings suggest doctors should rethink the standard practice of HIV treatment, a team reports at a meeting of microbiologists and infectious disease researchers

13

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

jerry submitted, created time 1 month 1 week (www.cell.com)

Human Immunodeficiency Viruses (HIV-1 and HIV-2) rely upon host-encoded proteins to facilitate their replication. Here, we combined genome-wide siRNA analyses with interrogation of human interactome databases to assemble a host-pathogen biochemical network containing 213 confirmed host cellular factors and eleven HIV-1-encoded proteins. Protein complexes that regulate ubiquitin conjugation, proteolysis, DNA-damage response, and RNA splicing were identified as important modulators of early-stage HIV-1 infection

7

Study Shows Weak Circumcision/HIV Benefit for Gay/Bisexual Men

jerry submitted, created time 1 month 2 weeks (www.webmd.com)

Although circumcision has been shown to reduce rates of HIV transmission among heterosexual couples, circumcision offers little HIV protection to gay/bisexual men -- overall. But it might cut HIV risk in predominantly insertive partners.

9

In the glow of the prize, Nature revisits the brawl

Darkfrog submitted, created time 1 month 2 weeks (www.nature.com)

What does HIV have in common with calculus? The dogfight over who discovered it.

This is a copy of Nature magazine's 1987 editorial on the dispute between the (U.S.) National Cancer Institute's Dr. Robert Gallo and the (French) Pasteur Institute's Françoise Barré-Sinoussi and Luc Montagnier--a conflict only slightly dramatized in the nonfiction novel and film "And the Band Played On."

In 1983, Montagnier brought samples of viral isolate to the NCI so that Gallo's lab could examine them

7

A Viral Blast from the Past

sea-maid submitted, created time 1 month 2 weeks (sciencenow.sciencemag.org)

Fifty-year-old sample sheds light on when HIV jumped from chimps to humans.

7

Tissue sample suggests HIV has been infecting humans for a century

sea-maid submitted, created time 1 month 2 weeks (www.nature.com)

Tissue samples from the fifties and sixties, taken from patients living in Kinshasa (then Leopoldville) in the Democratic Republic of Congo indicate that HIV, which was first recognized in the 1980's. Researchers were able to pluck chinks of viral DNA from the crudely preserved samples. Comparing the levels of genetic variation allowed them to give an estimate of HIV-1's year of origin: 1908.

This does not show us how HIV crossed from chimpanzees into humans, but it does give us a better idea of where to look for the disease's origins.

10

HIV in the U.S. hits American blacks extra hard

Darkfrog submitted, created time 2 months 1 week (www.nytimes.com)

The CDC has released a report on the way HIV spreads in the United States. Again, American blacks are at disproportionately high risk. While caucasian gay and bisexual men tend to get infected int heir thirties and forties, black gay and bisexual men tend to get infected in their teens and twenties.

The writeup does not say whether they adjusted for socioeconomic factors, but they do assert that the infected blacks were no more likely to be drug users or to engage in risky sexual behaviors than their counterparts in other races

9

HIV spreads in NYC at three times the U.S. average

kavin submitted, created time 2 months 3 weeks (www.reuters.com)

New Yorkers are contracting HIV at three times the national rate, the city health department said on Wednesday, attributing the difference to New York's large population of high-risk groups such as gay men and blacks.

In 2006, seventy-two of every 100,000 New Yorkers became infected with HIV, the virus that causes AIDS, compared with the national average of twenty-three infections, the health department said.

Some 4,800 people contracted HIV in 2006 in New York, long considered the epicenter of the U.S. HIV/AIDS epidemic

6

Studies show that behavior modification works in the fight against AIDS

Darkfrog submitted, created time 3 months 2 weeks (www.nytimes.com)

When I first read this headline, I thought that "behavior modification" meant only telling people to stop having sex, but it seems that delaying sex, using condoms and stopping drug abuse are here considered behavior modification as well.

"One is misplaced pessimism about the effectiveness of H.I.V. prevention strategies. A second is confusing the difficulty in changing human behavior with an inability to do so." Yeah, sing it! "They won't stop having sex just because we tell them to," does seem to be the assumption on the liberal side. It seems that, in this case, humility is misplaced.

8

The end of AIDS is nowhere in sight

sea-maid submitted, created time 3 months 2 weeks (www.nature.com)

The seventeenth annual AIDS conference opened in Mexico City last week. The consensus among the attendees seems to be that the failed vaccines, poorly targeted prevention measures and lack of fresh research talent all add up to years and years of HIV and AIDS in our future.

8

Black Americans have higher rates of HIV than some African countries

Darkfrog submitted, created time 3 months 3 weeks (www.nytimes.com)

According to the Black AIDS Institute, the United States may have a lower incidence of HIV than other countries overall, but U.S. blacks, considered alone, aren't so lucky. With 600,000 African-Americans living with HIV and 30,000 new infections each year, if American blacks were a country on their own, they would rank sixteenth worldwide. What's more, infected blacks are much more likely to die than infected whites, after adjusting for age (the article does not say that it adjusted for socioeconomic status)

5

Parasitic worms may help fuel AIDS epidemic: study

kavin submitted, created time 3 months 3 weeks (www.reuters.com)

People infected with parasitic worms may be much more susceptible to the AIDS virus, according to a study published on Tuesday that may help explain why HIV has hit sub-Saharan Africa particularly hard.

The study involving monkeys demonstrated how a type of parasitic worm that causes schistosomiasis, which affects 200 million people globally, may make HIV infection more likely.

Much lower amounts of the AIDS virus--seventeen times lower--were needed to cause infection in monkeys who had the parasitic worms than in the parasite-free monkeys, the researchers said

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