New Pathway for Malaria Infection Discovered

sea-maid submitted, created time 2 months 1 week (www.sciencedaily.com)

Cenix BioScience GmbH, a leading specialist in advanced RNA interference (RNAi)-based research services, Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, and the Lisbon-based biomedical research centre Instituto de Medicina Molecular (IMM), have announced the publication of their collaborative study in Cell Host & Microbe, describing the discovery and in vivo validation of scavenger receptor BI (SR-BI), a major regulator of cholesterol uptake by the liver, as a critical host factor for malaria infection.

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Malaria -- Effective insecticide-repellent synergy against mosquito vectors

bianjie submitted, created time 1 year 4 months (www.eurekalert.org)

IRD researchers and their partners devised a new control strategy against Anopheles gambiae, Africa's principal malaria vector. This involves a combination of a non-pyrethroid insecticide (propoxur) with a repellent (DEET). This mixture, impregnated into mosquito nets, proved more effective than the straightforward addition of their activities, as a strong synergy appeared between the two components.

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