Antibacterial drugs: New paths to beating bacteria

sea-maid submitted, created time 1 year 10 months (www.nature.com)

The need for new drugs to combat multidrug-resistant bacteria remains pressing. Now, two recent papers published in Science describe novel agents that target different mechanisms to currently approved antibacterials, which may help tackle this challenge.

The first study, by Haydon and colleagues, set out to target bacterial cell division. FtsZ is an essential bacterial protein that undergoes GTP-dependent polymerization to form the Z ring — the site of cell division — promoting the sequential recruitment of additional proteins that are vital to the process

2 comments | Blog It | Email It | Keywords: antibiotic resistance antibacterial targets FtsZ QseC antibiotic-resistant bacteria Z-ring antibacterials multidrug resistance multidrug-resistant bacteria