Articles with the keyword: 
Phage therapy gets a revival in the age of genetic engineering
sea-maid submitted, created time 1 year 6 months (www.nature.com)
A new engineered virus has shown itself able to render E. coli more susceptible to antibiotics and DNA-damaging drugs.
The virus in question is a bacteriophage, a virus that preys on bacteria (as opposed to multicellular organisms) naturally. Bacteriophages were once used therapeutically in the Soviet Union, but the treatment did not carry over to the West before the rise of antibiotics, at which time, bacteriophage cocktails were eclipsed. In 2006, however, the U.S. FDA approved one type of bacteriophage to be sprayed onto lunch meats 
Bacterial Infections in Hospitals Decline
sea-maid submitted, created time 1 year 6 months (www.time.com)
Stories about killer bacteria ravaging your child's school gym, locker rooms and nursing homes have made for grabby headlines in recent years. But the truth is that such life-threatening infections with MRSA, or methicillin-resistant Staphylococcus aureus, are still largely confined to certain hospital settings, rather than the community at large. And even in the highest-risk health-care environments, according to a new report, the threat of MRSA infection is diminishing.
Structure mediating spread of antibiotic resistance identified
piggy submitted, created time 1 year 8 months (www.eurekalert.org)
Scientists have identified the structure of a key component of the bacteria behind such diseases as whooping cough, peptic stomach ulcers and Legionnaires' disease. The research, funded by the Wellcome Trust and the Biotechnology and Biological Sciences Research Council (BBSRC), sheds light on how antibiotic resistance genes spread from one bacterium to another. The research may help scientists develop novel treatments for these diseases and novel ways to curtail the spread of antibiotic resistance
"Zinc Zipper" Plays Key Role in Hospital-acquired Infections
piggy submitted, created time 1 year 9 months (www.sciencedaily.com)
Hospital-acquired infections that are resistant to traditional antibiotic treatment have become increasingly common in recent years, confounding health care professionals and killing thousands of patients in the U.S. alone.
Now, in studies that could lead to new ways to prevent this growing public health danger, a team of University of Cincinnati (UC) researchers is exploring a “zinc zipper” that holds bacterial cells together and plays a key role in such infections.
Hospital-acquired infections affect about 1
Antibacterial drugs: New paths to beating bacteria
sea-maid submitted, created time 1 year 10 months (www.nature.com)
The need for new drugs to combat multidrug-resistant bacteria remains pressing. Now, two recent papers published in Science describe novel agents that target different mechanisms to currently approved antibacterials, which may help tackle this challenge.
The first study, by Haydon and colleagues, set out to target bacterial cell division. FtsZ is an essential bacterial protein that undergoes GTP-dependent polymerization to form the Z ring — the site of cell division — promoting the sequential recruitment of additional proteins that are vital to the process
CDC Campaign Targets MRSA Infections
jerry submitted, created time 1 year 11 months (health.usnews.com)
A national campaign to teach parents how to protect kids from skin infections caused by dangerous methicillin-resistant Staphylococcus aureus (MRSA) bacteria was launched this week by the US Centers for Disease ...
Gentle approach could cripple drug-resistant bugs
sea-maid submitted, created time 2 years 2 weeks (www.newscientist.com)
Taking a softly, softly approach to wiping out infection might be the way to beat the evolution of drug resistance in bacteria.
This new technique involves blocking the tularaemia bacterium's ability to sense human hormones. Although testing in human subjects is at least five years off, the bacteria's ability to kill mice was "crippled" by the alterations.
Resistance to drugs responsible for half of deaths from infections
sea-maid submitted, created time 2 years 3 months (www.bmj.com)
Multidrug resistant bacteria are responsible for about half of the 37,000 deaths a year in the 27 member states of the European Union that are caused by infections associated with health care, show the preliminary results of research from the European Centre for Disease Prevention and Control in Stockholm.
Antibiotic Alligator: Promising proteins lurk in reptile blood
jiangyun submitted, created time 2 years 4 months (www.sciencenews.org)
Researchers hunting for new antibiotics might get some aid from gator blood. Scientists are zeroing in on snippets of proteins found in American alligator blood that kill a wide range of disease-causing microbes and bacteria, including the formidable MRSA or methicillin-resistant Staphylococcus aureus.
DNA Pollution May Be Spawning Killer Microbes
Sue Wu submitted, created time 2 years 6 months (discovermagazine.com)
Rogue genetic snippets spread antibiotic resistance all over the environment. But where do they come from in the first place?
Drug-Resistant Flu Virus on the Rise
Sue Wu submitted, created time 2 years 7 months (www.time.com)
This winter's most common flu strain is showing resistance to the frontline anti-flu treatment, new data shows.
What makes one bacterium so deadly
yangjane submitted, created time 2 years 9 months (www.sciencenews.org)
Scientists have discovered some of the most aggressive antibiotic-resistant staph infections gain their advantage with a molecule that punctures the immune cells trying to fight off the bacteriaCommunity-associated MRSA (CA-MRSA). Understanding the role of this molecule in methicillin-resistant Staphylococcus aureus (MRSA) could lead to new therapies for the notoriously hard-to-treat, and sometimes fatal, skin infection.
This article is about antibiotic-resistant staph infections. It give us a question how to use antibiotic and how to prevent the Staphylococcus aureus.
HIV and TB emerge as African epidemic
biosunny submitted, created time 2 years 10 months (www.upi.com)
CAPE TOWN, South Africa, Nov. 2 (UPI) -- Cape Town, South Africa, is among the worst cities in the region affected by a epidemic of HIV and drug-resistant tuberculosis.
The BBC in Cape Town reported that children in the city’s slums are 100 times more likely to contract TB than elsewhere in the world.
Clonal success of piliated penicillin nonsusceptible pneumococci
bianjie submitted, created time 3 years 1 month (www.pnas.org)
Antibiotic resistance in pneumococci is due to the spread of strains belonging to a limited number of clones. The Spain9V-3 clone of sequence type (ST)156 is one of the most successful clones with reduced susceptibility to penicillin [pneumococci nonsusceptible to penicillin (PNSP)].
New strategies for combating multidrug-resistant bacteria
red monkey submitted, created time 3 years 2 months (www.sciencedirect.com)
"Antibiotic resistance is a problem that continues to challenge the healthcare sector. In particular, multidrug resistance is now common in familiar pathogens such as Staphylococcus aureus and Mycobacterium tuberculosis, as well as emerging pathogens such as Acinetobacter baumannii. New antibiotics and new therapeutic strategies are needed to address this challenge. Advances in identifying new sources of antibiotic natural products and expanding antibiotic chemical diversity are providing chemical leads for new drugs
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