Articles with the keyword: 
Genes for Synthesizing Thiostrepton Identified
sea-maid submitted, created time 1 year 5 months (www.sciencedaily.com)
Researchers at the Georgia Institute of Technology have identified the genetic machinery responsible for synthesizing thiostrepton, a powerful antibiotic produced by certain bacteria. Though effective against the dangerous MRSA (methicillin-resistant Staphylococcus aureus) and vancomycin-resistant enterococci, thiostrepton currently has only limited applications in humans because it is not water soluble. 
Advice to Vultures: Avoid Spanish Livestock
sea-maid submitted, created time 1 year 5 months (sciencenow.sciencemag.org)
Eating carcasses of livestock treated with antibiotics is wreaking havoc on the health of Spanish vultures, a new study carried out in Spain suggests. The researchers say that the practice of feeding vultures livestock carrion--although promoted by bird lovers--may actually threaten the species and should be ended.
Data collected from seventy-one nestlings from carrion-dependent areas suggest that the antibiotics used in meat production both collect in the vultures' bodies and inhibit their immune systems
No Hiding Place for Infective Bacteria
sea-maid submitted, created time 1 year 5 months (www.sciencedaily.com)
Scientists in Colorado have discovered a new approach to prevent bacterial infections from taking hold. Writing in the Journal of Medical Microbiology, Dr. Quinn Parks and colleagues describe how they used enzymes against products of the body's own defense cells to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm which enables them to avoid both the body's immune mechanisms and antibiotics.
Bacteria-Killing Enzyme Cures Mice of Fatal Pneumonia
sea-maid submitted, created time 1 year 5 months (www.sciencedaily.com)
Before the advent of antibiotics, pneumonia claimed so many lives and was so feared that it was called the “captain of the ship of death.” Now, at a time when new antibiotics have proved futile against resistant strains of bacteria, researchers at Rockefeller University are using a different tactic to keep this ship at bay.
Phage therapy gets a revival in the age of genetic engineering
sea-maid submitted, created time 1 year 6 months (www.nature.com)
A new engineered virus has shown itself able to render E. coli more susceptible to antibiotics and DNA-damaging drugs.
The virus in question is a bacteriophage, a virus that preys on bacteria (as opposed to multicellular organisms) naturally. Bacteriophages were once used therapeutically in the Soviet Union, but the treatment did not carry over to the West before the rise of antibiotics, at which time, bacteriophage cocktails were eclipsed. In 2006, however, the U.S. FDA approved one type of bacteriophage to be sprayed onto lunch meats
New Family of Antibacterial Agents Uncovered
sea-maid submitted, created time 1 year 7 months (www.sciencedaily.com)
As bacteria resistant to commonly used antibiotics continue to increase in number, scientists keep searching for new sources of drugs. One potential new bactericide has now been found in the tiny freshwater animal Hydra.
Antibiotics before infections save lives
sea-maid submitted, created time 1 year 8 months (www.reuters.com)
Giving antibiotics to patients in intensive care units as a precaution saves lives, according to a major Dutch study published Wednesday.
"Zinc Zipper" Plays Key Role in Hospital-acquired Infections
piggy submitted, created time 1 year 9 months (www.sciencedaily.com)
Hospital-acquired infections that are resistant to traditional antibiotic treatment have become increasingly common in recent years, confounding health care professionals and killing thousands of patients in the U.S. alone.
Now, in studies that could lead to new ways to prevent this growing public health danger, a team of University of Cincinnati (UC) researchers is exploring a “zinc zipper” that holds bacterial cells together and plays a key role in such infections.
Hospital-acquired infections affect about 1
Antibiotics Largest Cause of Drug-Induced Liver Damage
sea-maid submitted, created time 1 year 9 months (health.msn.com)
MONDAY, Dec. 1 (HealthDay News) -- Antibiotics are the single largest class of drugs that cause idiosyncratic drug-induced liver injury (DILI), researchers say.
The condition accounts for about thirteen percent of cases of acute liver failure in the United States and is the most common cause of death from acute liver failure.
DILI is caused by a wide range of prescription and nonprescription medications, nutritional supplements and herbal products
Long-Term Antibiotic Use Affects "Good" Gut Bacteria
sea-maid submitted, created time 1 year 9 months (health.yahoo.com)
Antibiotic treatment, especially when prolonged or repeated, may have a negative impact on beneficial bacteria that live in the gut, according to a new study.
Gut bacteria play helpful roles in various aspects of human nutrition, metabolism and immune responses, experts note.
Researchers focused on the widely-used antibiotic ciprofloxacin, prescribed for a number of bacteria-caused conditions, including urinary tract infections. It has been believed that ciprofloxacin causes only modest harm to beneficial bacteria in the body.
In this study, Stanford University's Dr
Follow-up data on the effects of antibiotics in pregnant women
jerry submitted, created time 1 year 10 months (www.thelancet.com)
Long-term follow-up data on the effects of antibiotics in pregnant women experiencing premature labour and the developmental effects on their children are published in the ORACLE children study. The original trial published in 2001 investigated the effect of two antibiotics given around preterm labor. The follow-up findings have important implications for the clinical management of pregnant women experiencing preterm birth......
Gentle approach could cripple drug-resistant bugs
sea-maid submitted, created time 2 years 1 week (www.newscientist.com)
Taking a softly, softly approach to wiping out infection might be the way to beat the evolution of drug resistance in bacteria.
This new technique involves blocking the tularaemia bacterium's ability to sense human hormones. Although testing in human subjects is at least five years off, the bacteria's ability to kill mice was "crippled" by the alterations.
New antibiotic beats superbugs at their own game
kavin submitted, created time 2 years 2 months (esciencenews.com)
The problem with antibiotics is that, eventually, bacteria outsmart them and become resistant. But by targeting the gene that confers such resistance, a new drug may be able to finally outwit them. Rockefeller University scientists tested the new drug, called Ceftobiprole, against some of the deadliest strains of multidrug-resistant Staphylococcus aureus (MRSA) bacteria, which are responsible for the great majority of staphylococcal infections worldwide, both in hospitals and in the community
The emergence of Stenotrophomonas maltophilia ...exaggerated
sea-maid submitted, created time 2 years 2 months (www.bmj.com)
Headlines about S maltophilia, including "no antibiotics can stop it" and "rising death toll in hospitals" are unfounded, write Georgia Duckworth and Alan Johnson, from the Health Protection Agency's Centre for Infections in London. In fact, they say, S maltophilia infections are relatively rare compared to infections caused by bacteria such as meticillin resistant Staphylococcus aureus (MRSA).
Resistance to drugs responsible for half of deaths from infections
sea-maid submitted, created time 2 years 2 months (www.bmj.com)
Multidrug resistant bacteria are responsible for about half of the 37,000 deaths a year in the 27 member states of the European Union that are caused by infections associated with health care, show the preliminary results of research from the European Centre for Disease Prevention and Control in Stockholm.
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