Researchers discover that growing up too fast may mean dying young in honey bees

sea-maid submitted, created time 6 days 21 hours (www.biologynews.net)

Reactive oxygen species (ROS) occur as a by-product of aerobic metabolism and impair cellular function by damaging proteins, nucleotides and lipids. Organisms possess a variety of anti-oxidant mechanisms to mitigate the effects of ROS, and the oxidative stress model of aging and senescence suggests that physiological performance declines with age due to lifetime accrual of ROS-induced damage and progressively limited anti-oxidant capacity

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High consumption of coffee or tea every day appears to protect male smokers against at least one type of stroke

kavin submitted, created time 3 months 4 days (www.medscape.com)

This large, prospective, observational study showed that Finnish smokers who consumed eight or more cups of coffee per day had a 23% lowered risk for cerebral infarction, whereas those who drank two or more cups of black tea daily had a 21% lowered risk for this type of stroke vs those who drank little or none of these beverages. The associations were independent of risk factors such as a history of coronary heart disease.

Their report is published in the June 2008 issue of Stroke

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Mitochondrial Mutations Make Tumors Spread

jane2007 submitted, created time 6 months 2 days (sciencenow.sciencemag.org)

Why is it that cancer often strikes its final, fatal blow when a tumor spreads to other organs? It's because of the metastasis of mitochondrial DNA mutations.

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Antioxidants can change fish behaviour

jane2007 submitted, created time 10 months 4 weeks (www.nature.com)

Antioxidants are all the rage, with research suggesting that they may help to prevent cancer, strokes and heart disease. Now a study highlights how these oxygen-mopping compounds affect more than just cellular health: they also seem to effect behaviour.

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Study: Antioxidants May Provide DNA Radiation Protection Too

yangjane submitted, created time 11 months 4 hours (www.scientificblogging.com)

Two common dietary molecules found in legumes and bran could protect DNA from the harmful effects of radiation, researchers from the University of Maryland report.

Inositol and inositol hexaphosphate (IP6) protected both human skin cells and a skin cancer-prone mouse from exposure to ultraviolet B (UVB) radiation, the damaging radiation found in sunlight, the team reported today at the American Association for Cancer Research Centennial Conference on Translational Cancer Medicine.

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Antioxidants may protect against knee arthritis

DanyC submitted, created time 1 year 2 months (www.reutershealth.com)

According to a new study, people who have diets with plenty of foods containing antioxidants may be protecting themselves from bone changes associated with knee arthritis.

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Diet and Risk of Ovarian Cancer in the California Teachers Study Cohort

fiona submitted, created time 1 year 6 months (aje.oxfordjournals.org)

Dietary phytochemical compounds, including isoflavones and isothiocyanates, may inhibit cancer development but have not yet been examined in prospective epidemiologic studies of ovarian cancer. The authors have investigated the association between consumption of these and other nutrients and ovarian cancer risk in a prospective cohort study.

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Acetylcysteine and Probucol Alter the Activity of Endogenous Antioxidant Enzyme Activity

biscuits submitted, created time 1 year 6 months (www.arcmedres.com)

Antioxidants such as N-acetylcysteine and probucol have been used to protect patients from contrast media-induced nephrotoxicity. These findings suggest that the renal protective effects of acetylcysteine and probucol against contrast-induced oxidative stress and nephrotoxicity may be mediated by altering endogenous GPx activity.

Submit comment | Blog It | Email It | Keywords: Antioxidants Contrast media Glutathione peroxidase Superoxide dismutase Diabetes Nephrotoxicity

Tropospheric Ozone Toxicity vs. Usefulness of Ozone Therapy

biscuits submitted, created time 1 year 7 months (www.arcmedres.com)

There is a general consensus that continuous inhalation of air polluted with ozone is detrimental for the lungs and vital organs. Even if the concentration of tropospheric ozone is slightly above the tolerated dose, toxicity ensues owing to the cumulative dose inhaled for months. However, in medicine ozone is used as a real drug and a precise concentration and therapeutic dosage must be calibrated against the antioxidant capacity of blood. As ozone reacts with blood, it generates pharmacological messengers such as H2O2 and lipid oxidation products (LOPs)

Submit comment | Blog It | Email It | Keywords: Ozone therapy Antioxidants Oxidative stress Heme-oxygenase-1 Ozone tolerance