Articles with the keyword:
6

Too Old, Too Fast

sumsung submitted, created time 8 months 2 weeks (sciencenow.sciencemag.org)

Researchers have unearthed new clues behind a disease that effectively turns young children into senior citizens. A protein called progerin prods stem cells to go astray, causing them to mature into the wrong cell types. The findings may have implications for understanding normal aging as well.

6

Study reveals a key to blood vessel growth and possible drug target

davis submitted, created time 1 year 1 month (www.eurekalert.org)

Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels. The finding not only offers an important insight into the development of the vascular system during embryonic development but suggests a potential target for inhibiting the blood vessels that fuel cancers, diabetic eye complications and atherosclerosis, the researchers say.

12

Early Rise in Serum VEGF and PDGF Levels Predisposes Patients With a Normal MBL2 Genotype to Restenosis After Eversion Endarterectomy

Reviver submitted, created time 1 year 3 months (stroke.ahajournals.org)

"These findings indicate that the development of restenosis depends on both complement activation regulated by the MBL2 gene and pathologic processes leading to enhanced production of VEGF and PDGF during the very early postoperative period."

12

Diesel Fumes Help Clog Arteries

diefish submitted, created time 1 year 3 months (health.usnews.com)

Scientists say they've spotted the biochemical process that makes diesel exhaust so dangerous to human arteries.This process accelerates atherosclerosis -- a buildup of fatty deposits that can eventually lead to complete vessel blockage, according to the study in the July 26 online issue of Genome Biology.

12

Air pollution link to clogged arteries

sumsung submitted, created time 1 year 3 months (www.eurekalert.org)

Should we be watching our exposure to airborne pollution as well as our cholesterol levels? Research now indicates that air pollution has a role to play in atherosclerosis (artery hardening), which can contribute to heart attacks or strokes.

5

Estrogen is safe for most, new study finds

Reviver submitted, created time 1 year 5 months (www.chron.com)

The latest piece of evidence, in today's New England Journal of Medicine, shows that taking estrogen for seven years or more after menopause reduces calcification of the arteries — one of the key indicators of atherosclerosis — by as much as 60 percent. High levels of calcification are generally considered a predictor of increased risk for a heart attack.

5

Drug Protects Against Diabetes And Atherosclerosis In Mice

dovechocolate submitted, created time 1 year 5 months (www.sciencedaily.com)

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online at Nature on June 6, 2007.

5

Race-Gender Differences in the Association of Trait Anger with Subclinical Carotid Artery Atherosclerosis

badboy submitted, created time 1 year 5 months (aje.oxfordjournals.org)

"Sociodemographic, lifestyle, anthropometric, and biologic cardiovascular disease risk factors appear to mediate the relation in Black women, White men, and White women. In conclusion, these findings document disparate race-gender patterns in the association of trait anger with subclinical carotid artery atherosclerosis.
"

5

Polymorphism in microsomal triglyceride transfer protein: A link between liver disease and atherogenic postprandial lipid profile in NASH?

julie submitted, created time 1 year 6 months (www3.interscience.wiley.com)

"MTP -493 G/T polymorphism may impact NASH by modulating postprandial lipemia and lipoprotein metabolism; homozygous GG carriers have a more atherogenic postprandial lipid profile than the other genotypes, independently of adipokines and insulin resistance."

5

Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation

athena submitted, created time 1 year 7 months (diabetes.diabetesjournals.org)

"Obesity is linked to a variety of metabolic disorders, such as insulin resistance and atherosclerosis. Dysregulated production of fat-derived secretory factors, adipocytokines, is partly responsible for obesity-linked metabolic disorders."

6

Granulocyte Colony-Stimulating Factor and Granulocyte Macrophage Colony-Stimulating Factor Exacerbate Atherosclerosis in Apolipoprotein E-Deficient Mice

fiona submitted, created time 1 year 7 months (circ.ahajournals.org)

"Recent studies have suggested a potential contribution of bone marrow-derived progenitor cells to vascular repair. Preliminary clinical studies have explored the possibility that mobilization of progenitor cells with granulocyte macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) can affect vascular repair. However, it is not known whether the short-term administration of G-CSF or GM-CSF exerts beneficial effects on atherosclerosis."

6

Paraoxonase-2 Reduces Oxidative Stress in Vascular Cells and Decreases Endoplasmic Reticulum Stress-Induced Caspase Activation

fiona submitted, created time 1 year 7 months (circ.ahajournals.org)

"In the vascular system, elevated levels of reactive oxygen species (ROS) produce oxidative stress and predispose to the development of atherosclerosis. Therefore, it is important to understand the systems producing and those scavenging vascular ROS. Here, we analyzed the ROS-reducing capability of paraoxonase-2 (PON2) in different vascular cells and its involvement in the endoplasmic reticulum stress pathway known as the unfolded protein response."

6

Cathepsin L Deficiency Reduces Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Knockout Mice

fiona submitted, created time 1 year 7 months (circ.ahajournals.org)

"Cat L directly participates in atherosclerosis by degrading elastin and collagen and regulates blood-borne leukocyte transmigration and lesion progression."

6

High Blood Pressure in Pregnancy and Coronary Calcification

medal submitted, created time 1 year 7 months (hyper.ahajournals.org)

"A considerable proportion of pregnant women develop high blood pressure in pregnancy. Although it is assumed that this condition subsides after pregnancy, many of these women develop the metabolic syndrome later in life and are at increased risk to develop coronary heart disease."

7

Regions of low endothelial shear stress are the sites where coronary plaque progresses and vascular remodelling occurs in humans: an in vivo serial study

julie submitted, created time 1 year 7 months (eurheartj.oxfordjournals.org)

"Plaque progresses in subsegments with low ESS, associated with either constrictive or expansive remodelling. Different mechanisms are likely responsible for expansive remodelling in different local vascular environments. Early in vivo identification of arterial subsegments likely to develop high-risk plaque characteristics may allow for selective interventions to avoid adverse cardiac outcomes. "

\ 1 \
Report Abuse
abuse@discover8.com
pRNATin-H1.4/Retro
A synthetic peptide corresponding to residues 410 through 41 ...
www.genscript.com
Express PAGE Gel
Gels : Express PAGE Gel
www.genscript.com
5M QuickBlock Kit
5M QuickBlock Kit
www.genscript.com
Rabbit Anti cdc25C (Ab-216) (polyclonal)
antibody : Rabbit Anti cdc25C (Ab-216) (polyclonal) ...
www.genscript.com