Intermittent Tacrolimus Ointment Therapy Helps Prevent Relapse of Stabilized Atopic Dermatitis

kavin submitted, created time 4 months 2 weeks (www.medscape.com)

NEW YORK (Reuters Health) Jun 23 - In patients with stabilized atopic dermatitis, intermittent therapy with tacrolimus ointment was associated with significantly more flare-free days and longer time to first relapse compared with vehicle alone, according to a report in the June issue of the Journal of the American Academy of Dermatology.

Tacrolimus is a topical calcineurin inhibitor (TCI) and is manufactured in ointment form under the brand name Protopic by Astellas Pharma US Inc., which supported this multicenter study by U.S. researchers

2 comments | Blog It | Email It | Keywords: Tacrolimus Ointment Therapy patients dermatology Intermittent Tacrolimus Ointment Therapy atopic dermatitis

Atopic Dermatitis

Vincent submitted, created time 7 months 2 weeks (content.nejm.org)

Atopic dermatitis, or eczema, is a common skin disease that is often associated with other atopic disorders, such as allergic rhinitis and asthma 1. The clinical manifestations of atopic dermatitis vary with age; three stages can often be identified. In infancy, the first eczematous lesions usually emerge on the cheeks and the scalp. Scratching, which frequently starts a few weeks later, causes crusted erosions. During childhood, lesions involve flexures, the nape, and the dorsal aspects of the limbs. In adolescence and adulthood, lichenified plaques affect the flexures, head, and neck

2 comments | Blog It | Email It | Keywords: skin eczema human skin diseases atopic dermatitis

Quality of life is severely compromised in adult patients with atopic dermatitis in Brazil, especially due to mental components

gh0706 submitted, created time 1 year 4 months (www.ncbi.nlm.nih.gov)

To measure the quality of life (QoL), either by a specific dermatology or generic self applied questionnaire, in Atopic dermatitis adult Brazilian patients, looking for selected affected groups. The researchers studied the quality of life of 75 Brazilian ambulatory adults with atopic dermatitis using two types of self-answered instruments: a quality of life generic questionnaire (SF-36) and a 10-item Dermatology Life Quality Index (DLQI) questionnaire. All patients had been treated for at least 6 months, and their disease status was determined by Eczema Area and Severity Index scores

Submit comment | Blog It | Email It | Keywords: Atopic dermatitis Dermatology Quality questionnaire

Prevention of allergic disease during childhood by allergen avoidance

BIOBOSS submitted, created time 1 year 8 months (www.jacionline.org)

Early life allergen exposure may increase the risk of childhood allergy, but the protective effect of reduction in allergen exposure remains uncertain. Recently, The researchers found allergic diseases can be reduced, for at least the first 8 years of life, by combined food and HDM allergen avoidance in infancy.

Submit comment | Blog It | Email It | Keywords: Atopy allergy asthma rhinitis atopic dermatitis food allergy prevention diet house dust mite randomized controlled trial