Articles with the keyword: 
Towards the Virtual Screening Technique: Trends and Updates
yarmoluk submitted, created time 2 weeks 5 days (www.otavachemicals.com)
One of the leading Ukrainian companies, OTAVA Ltd. develops its own virtual screening system. 
A new way to identify disease associated genes
jerry submitted, created time 1 month 4 weeks (www.biodatamining.org)
A new algorithm, which mines databases of tissue specificity, gene connectivity and disease association, has identified a new group of genes that interact with disease-causing genes and impact on disease outcomes.
TGen investigators devise faster, cheaper way of analyzing the human genome
sea-maid submitted, created time 2 months 6 days (esciencenews.com)
Investigators at the Translational Genomics Research Institute (TGen) today announced a faster and less expensive way for scientists to find which genes might affect human health.
Computational Systems Analysis of Dopamine Metabolism
jerry submitted, created time 4 months 2 weeks (www.plosone.org)
A prominent feature of Parkinson's disease (PD) is the loss of dopamine in the striatum, and many therapeutic interventions for the disease are aimed at restoring dopamine signaling. Dopamine signaling includes the synthesis, storage, release, and recycling of dopamine in the presynaptic terminal and activation of pre- and post-synaptic receptors and various downstream signaling cascades
sumsung submitted, created time 8 months 7 hours (sciencenow.sciencemag.org)
Researchers have developed a computer algorithm that can identify some plant species according to their unique sonar echoes. The experiments were meant to help biologists understand how bats find their favorite fruits or insects, but the research might also help engineers design high-speed systems to identify everything from widgets on conveyor belts to faces in crowds.
Ukrainian company Otava develop novel casein kinase 2 (CK2) inhibitors as anticancer drugs.
yarmoluk submitted, created time 8 months 2 weeks (www.discover8.com)
Over the past few years our company, OTAVA Ltd., has designed novel, efficient at low micro molar concentrations, and selective CK2 inhibitors. To discover the new inhibitors, our researchers spanned computer-based molecular modeling with chemical synthesis of compounds which were further tested in vitro to investigate their ability to bind to and affect the activity of CK2.
Peer reviewing the modern-day matchmaker: online dating sites begin to publish studies
Darkfrog submitted, created time 9 months 3 weeks (www.nytimes.com)
eHarmony.com and Chemistry.com in particular are dying to be able to advertise their dating algorithms as "scientifically proven." And after years in the online dating market, they finally have enough data to perform, write and publish sociological studies.
But will these studies be the real thing? So far, eHarmony's only got one out there, despite having enough data for more. For all that these companies claim to want to be peer reviewed, I get the impression that they're being awfully selective with the information that they release.
The article brings up another interesting point
Study shows new way to fight Chagas disease
Eric wu submitted, created time 10 months 3 weeks (www.reuters.com)
A new, low-cost screening strategy could make it easier for poor countries to target and treat Chagas disease, a deadly parasite-borne condition found mainly in Latin America, according to a new study.
yangjane submitted, created time 1 year 3 hours (www.nature.com)
The Joint United Nations Programme on HIV/AIDS (UNAIDS) and the World Health Organization (WHO) released new statistics on the global prevalence of HIV and AIDS on 20 November. Their new report estimates that 33.2 million people worldwide are infected with HIV; in 2006 the estimate was 39.5 million.
According to the report, the 16% reduction in the estimate is the result of better data and better epidemiological interpretation of those data, particularly in India.
So Cute You Could Just Eat Them Up
Eric wu submitted, created time 1 year 6 days (sciencenow.sciencemag.org)
Most likely, your mother nurtured you for years and you never worried that when you came home from kindergarten, she'd gobble you up. But many animals do occasionally eat their young, including many that also are attentive parents. New research indicates that, when it comes to deciding whether to chow down on junior, Ma and Pa may be motivated by more than hunger. For example, parents may selectively eat their weaker offspring to favor the stronger ones, an evolutionary model predicts.
caGEDA: a web application for the integrated analysis of global gene expression patterns in cancer.
biomedguru submitted, created time 1 year 2 weeks (bioinformatics.upmc.edu)
This paper describes caGEDA, webware for the robust analysis of data from microarray gene expression studies. Users can upload their data and evaluate a myriad of options for data normalization, for finding differentially expressed genes, and for class prediction (diagnostic and prognostic modeling). caGEDA is unsual in the ease of use of its extensive resampling algorithms for method evaluation. caGEDA has numerous published cancer microarray data sets on tap. Users can begin exploring microarray data analysis immediately with only a browser.
Clinical decision modeling system
biomedguru submitted, created time 1 year 2 weeks (www.biomedcentral.com)
This paper describes the world's first software designed specifically to facilitate integrative translational research. Researchers using the software will be able to plan effective integrative clinical trials that examine the utility of specific clinical workflows that integrate biomarkers, imaging, clinical and demographic data.
The software is available online here:
http://bioinformatics.pitt.edu/software/cdms/
A constrained polynomial regression procedure for estimating the local False Discovery Rate
DanyC submitted, created time 1 year 4 months (www.biomedcentral.com)
"In the framework of estimating procedures without any distributional assumption under the alternative hypothesis, a new and efficient procedure for estimating the lFDR is described. The results of a simulation study indicated good performances for the proposed estimator in comparison to four published ones. The five different procedures were applied to real datasets."
The conserved transcriptome in human and rodent male gametogenesis
addict submitted, created time 1 year 6 months (www.pnas.org)
"We report a cross-species expression profiling analysis of the human, mouse, and rat male meiotic transcriptional program, using enriched germ cell populations, whole gonads, and high-density oligonucleotide microarrays (GeneChips)."
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angelfish
kavin
Sue Wu
jane2007
amino acid : Fmoc-L-Tyr(tBu)-OH
www.genscript.com
BacReady Multiplex PCR System
DNA Preparation/PCR System from Bacteria
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HEL (46-61)
peptide : HEL (46-61)
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RNase A, bovine
RNase A is purified from bovine pancreas. RNase A hydrolyzes ...
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