Articles with the keyword: 
New Evidence Of How High Glucose Damages Blood Vessels Could Lead To New Treatments
piggy submitted, created time 10 months 1 week (www.sciencedaily.com)
New evidence of how the elevated glucose levels that occur in diabetes damage blood vessels may lead to novel strategies for blocking the destruction, Medical College of Georgia researchers say.
They found a decreased ability of blood vessels to relax resulted from increased activity of a natural mechanism for altering protein form and function, says Dr. Rita C.Tostes, physiologist in the MCG School of Medicine.
The researchers suspect increased modification of proteins by a glucose-derived molecule is a player in vascular problems associated with hypertension, stroke and obesity as well. 
Building the lymphatic drainage system
piggy submitted, created time 10 months 3 weeks (www.eurekalert.org)
Our bodies' tissues need continuous irrigation and drainage. Blood vessels feeding the tissues bring in the fluids, and drainage occurs via the lymphatic system. While much is known about how blood vessels are built, the same was not true for lymph vessels. Now though, Norrmén et al. have identified two of the lead engineers that direct drainage construction in the mouse embryo.
The engineers are the transcription factors, Foxc2 and NFATc1
Tiny Tool to Control Growing Blood Vessels Opens New Potential in Tumor Research
sea-maid submitted, created time 1 year 2 weeks (www.sciencedaily.com)
Researchers at Uppsala University have developed a new tool that makes it possible to study the signals in the body that control the generation of blood vessels. The researchers’ findings, published in the new issue of Lab on a Chip, enable scientists to determine what signals in the body attract or repel blood vessels, knowledge that is extremely interesting in tumor research.
Innovative Method to Starve Tumors
sea-maid submitted, created time 1 year 1 month (www.sciencedaily.com)
The development of cancerous tumors is highly dependent on the nutrients the tumors receive through the blood. The team of Dr. Janusz Rak, of the Research Institute of the McGill University Health Centre (MUHC) at the Montreal Children's Hospital, including Dr. Khalid Al-Nedawi and Brian Meehan, has just discovered a new mechanism that tumors use to stimulate the growth of the blood vessels that feed them. The researchers have also proposed a new way to control this process, which may translate into future therapies.
Brain's Arteries Have a Mind of Their Own
piggy submitted, created time 1 year 1 month (sciencenow.sciencemag.org)
When studying the neurological basis for everything from how we deal with the loss of a loved one to why we crave certain foods, scientists have increasingly turned to functional magnetic resonance imaging (fMRI). As it's most often used, the technique measures blood oxygenation in the brain--and the assumption has always been that areas with more oxygenated blood are areas where neurons are busily firing away. But a new study suggests that's not always true, adding an unexpected wrinkle to this burgeoning field of research.
The surprising findings come from experiments with two monkeys
Control of blood vessels a possible weapon against obesity
piggy submitted, created time 1 year 2 months (www.eurekalert.org)
Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolize body fat more quickly, according to a new study from Karolinska Institutet. Scientists now hope to learn how to control blood vessel development in humans in order to combat obesity and diabetes.
The growth of fat cells and their metabolism depend on oxygen and blood-borne nutrients. A possible way to regulate the amount of body fat – in order, for instance, to combat obesity – can therefore be to affect the development of blood vessels in the adipose tissue
Starving tumors of blood vessels may not be the way to go
piggy submitted, created time 1 year 4 months (www.sciencedaily.com)
Dense networks of blood vessels thought to spur cancer’s growth could actually hinder rather than promote tumor progression, according to a new study at the University of California, San Diego.
The findings partly explain why drugs designed to treat cancer by strangling its blood supply have been disappointing when used alone and why those treatments are more effective when combined with traditional chemotherapy
Discovery of natural compounds that could slow blood vessel growth
sea-maid submitted, created time 1 year 5 months (esciencenews.com)
Using a whole-genome approach, researchers have found more than one hundred human protein compounds that can slow blood vessel growth. This could lead to treatments against diseases that depend on the growth of new blood vessels, including cancer, macular degeneration and rheumatoid arthritis.
sumsung submitted, created time 1 year 10 months (sciencenow.sciencemag.org)
A team of clinical trial specialists and consumer advocates has concluded that blood substitutes increase death rates by 30% and nearly triple the risk of heart attacks. Not everyone buys the findings, however, and clinical trials in the field continue.
How to print out a blood vessel
sumsung submitted, created time 2 years 6 hours (www.nature.com)
A tissue engineering group has succeeded in creating functional blood vessels and cardiac tissue, using a printer that dispenses cells instead of ink. The work, published this month in Tissue Engineering, is among the first to produce functional three-dimensional tissue using a printer, and a milestone on the way to the goal of printing out whole organs.
Tumor Time Bombs Set Off by Stem Cells
sumsung submitted, created time 2 years 2 months (www.sciam.com)
Researchers say they have identified a switch that makes dormant breast cancer cells that have traveled to the lungs swell to lethal proportions—completing the dreaded process of metastasis or cancer spread.
New risk factors discovered for Alzheimer's disease
bianjie submitted, created time 2 years 8 months (www.blackwellpublishing.com)
A recent study in Journal of Neuroimaging suggests that cognitively normal adults exhibiting atrophy of their temporal lobe or damage to blood vessels in the brain are more likely to develop Alzheimer's disease. Older adults showing signs of both conditions were seven-times more likely to develop Alzheimer's than their peers.
Engineered blood vessels function like native tissue
bianjie submitted, created time 2 years 8 months (www.buffalo.edu)
Blood vessels that have been tissue-engineered from bone marrow adult stem cells may in the future serve as a patient's own source of new blood vessels following a coronary bypass or other procedures that require vessel replacement, according to new research from the University at Buffalo Department of Chemical and Biological Engineering.
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