Articles with the keyword: 
In Long-Awaited Maps of Cancer, the Breakthrough Is the Problem
jerry submitted, created time 2 days 1 hour (online.wsj.com)
After struggling for years to improve the treatment of cancer, scientists now hope to fight the disease with the help of the same techniques that deciphered the human genome eight years ago: mapping it. The idea was to sort out which gene mutations cause which types of cancer so that cancer treatments could be tailored to each patient. However, what the researchers found was quite different... 
Regrets After Prostate Surgery
kavin submitted, created time 1 week 30 minutes (well.blogs.nytimes.com)
One in five men who undergoes prostate surgery to treat cancer later regrets the decision, a new study shows. Surprisingly, regret is highest among men who opt for robotic prostatectomy, a minimally invasive surgery that is growing in popularity as a treatment.
The research, published in the medical journal European Urology, is the latest to suggest that technological advances in prostate surgery haven’t necessarily translated to better results for the men on which it is performed
Taxanes May Increase Risk for Significant Psychological Symptoms
kavin submitted, created time 1 week 36 minutes (www.medscape.com)
Taxane-based chemotherapies are increasingly used for the adjuvant treatment of early and locally advanced breast cancer, but new research suggests that they confer a risk for significant psychologic symptoms. According to a study published in the August 1 issue of Cancer, patients who received taxane-based therapy had significantly worse emotional distress and slower psychologic recovery than those receiving a similar regimen without taxanes.
The researchers also observed high rates of probable clinical depression among patients who received taxane therapy
jerry submitted, created time 1 week 1 day (sciencenow.sciencemag.org)
A new study in lab mice suggests that cells may break off from a tumor even before they become cancerous, seeding the body with cells that evade detection and lie dormant for years before turning into tumors of their own.
sea-maid submitted, created time 1 week 2 days (www.nature.com)
Non-cancerous mammary cells in mice can take up residence in the lungs and later form tumors. This chance of residence, called metastasis, had previously been thought nearly impossible for ordinary, healthy cells.
Gene Identified for Deadly Childhood Cancer
sea-maid submitted, created time 1 week 4 days (sciencenow.sciencemag.org)
Fifteen years of genetic sleuthing have finally paid off: Researchers have nailed the gene that appears to cause an inherited form of neuroblastoma, a cancer of the nervous system that predominantly strikes children. Scientists are optimistic that the findings will allow them to develop disease screening for some families, as well as lead to potential new therapies.
Burning incense linked to respiratory cancers
sea-maid submitted, created time 1 week 5 days (www.reuters.com)
Burning incense may create a sweet scent, but regularly inhaling the smoke could put people at risk of cancers of the respiratory tract, researchers reported Monday.
Fatal tumors force early mating in Tasmanian devils
sea-maid submitted, created time 2 weeks 1 day (www.livescience.com)
In recent years, the population of these endangered marsupials has taken a huge hit. An infectious cancer, spread through biting, affects and kills devils over the age of two. However, the devils have compensated for this by reproducing earlier and earlier in their life cycle.
It isn't clear exactly why the animals are mating early. It might have something to do with the disease or it might simply be the result of reduced competition for food.
kavin submitted, created time 3 weeks 3 hours (www.medscape.com)
Four commonly used moisturizers promoted skin cancers in mouse studies.
Mice are not men. But the unexpected finding suggests that these — and perhaps other products — may not be as safe as they're thought to be.
The moisturizers tested in the study were Dermabase, Dermovan (a wholesale-only product discontinued in 2006), Eucerin Original Moisturizing Cream, and Vanicream.
In a mouse model of sun-related skin cancer, frequent application of each product resulted in more skin tumors and faster tumor growth, says study leader Allan H
Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway
sea-maid submitted, created time 3 weeks 10 hours (www.nature.com)
Fanconi anemia (FA) is a genome instability syndrome that is characterized by progressive bone marrow failure and a high risk of cancer. FA patients are particularly susceptible to leukemia as well as squamous cell carcinomas (SCCs) of the head and neck, anogenital region and skin. This article details experiments exploring the up and downregulation of FA.
Lung cancer screening: the way forward
sea-maid submitted, created time 3 weeks 10 hours (www.nature.com)
To take lung cancer screening into national programs, we first have to answer the question whether low-dose computed tomography (LDCT) screening and treatment of early lesions will decrease lung cancer mortality compared with a control group, to accurately estimate the balance of benefits and harms, and to determine the cost-effectiveness of the intervention.
Experimental chemotherapy regimen shows promise in treating advanced lung cancer
sea-maid submitted, created time 3 weeks 5 days (www.eurekalert.org)
A combination of chemotherapy agents that have been tested in other tumor types appears to be a promising alternative to standard treatment for advanced nonsmall cell lung cancer, according to a report in the Aug. 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.
New Life for a Discredited Treatment?
sea-maid submitted, created time 4 weeks 7 hours (sciencenow.sciencemag.org)
The long-dormant debate over vitamin C's usefulness for cancer therapy may be about to reignite. Researchers have found that injecting mice with high doses of the vitamin staved off tumor growth. The findings could upend the established view that vitamin C is useless as a cancer treatment.
sea-maid submitted, created time 1 month 10 hours (www.manchester.ac.uk)
University of Manchester researchers are investigating exactly how chemotherapy drugs kill cancerous tumors in a bid to reduce side effects and test the effectiveness of safer new agents.
Researchers unveil vital key to cancer
sea-maid submitted, created time 1 month 11 hours (www.manchester.ac.uk)
University of Manchester scientists have uncovered the 3D structure of Mps1 – a protein that regulates the number of chromosomes during cell division and thus has an essential role in the prevention of cancer – which will lead to the design of safer and more effective therapies.
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