Articles with the keyword: 
Gene Therapy Technique Thwarts Cancer By Cutting Off Tumor Blood Supply
sea-maid submitted, created time 1 year 2 months (www.sciencedaily.com)
University of Florida researchers have come up with a new gene therapy method to disrupt cancer growth by using a synthetic protein to induce blood clotting that cuts off a tumor's blood and nutrient supply. 
U-M researchers link pathway to breast cancer stem cells
piggy submitted, created time 1 year 3 months (www2.med.umich.edu)
A gene well known to stop or suppress cancer plays a role in cancer stem cells, according to a new study from the University of Michigan Comprehensive Cancer Center. The researchers found that several pathways linked to the gene, called PTEN, also affected the growth of breast cancer stem cells.
Further, by using a drug that interferes with that pathway, the researchers produced an up to 90 percent decrease in the number of cancer stem cells within a tumor.
Studies find new weaknesses in cancer
sea-maid submitted, created time 1 year 3 months (www.reuters.com)
Researchers using a new gene-scanning method have found a potential way to fight cancer by silencing genes that tumors need to stay alive
sea-maid submitted, created time 1 year 4 months (www.nature.com)
Bevacizumab, brand name Avastin, is the first anti-cancer drug designed specifically to starve tumors of blood. However, phase-three clinical trials seem to show that it is no more effective than chemotherapy alone.
There was a certain amount of industry drama associated with Avastin: Earlier this year Roche bought the company that produces it, Genentech, for $95 per share, a total of around $47 billion and a whole lot of nail-biting by Genentech employees, who value their company's freestyle corporate culture and feared that a takeover by Roche would stifle it
Designer immune cells fight prostate cancer
sea-maid submitted, created time 1 year 4 months (www.nature.com)
Genetically engineered immune cells may have helped two patients with advanced prostate cancer fight the disease, preliminary results suggest.
Possible Way to Block the Spread of Deadly Brain Tumors
sea-maid submitted, created time 1 year 4 months (www.sciencedaily.com)
Researchers at the Translational Genomics Research Institute (TGen) may have found a way to stop the often-rapid spread of deadly brain tumors.
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
Researchers from the University of Michigan Comprehensive Cancer Center have found a new way to examine brain tumor treatments. Their imaging system can predict probably patient longevity as early as one week after initial treatment.
Instead of creating a composite view of average change within the tumor, this method uses a standard magnetic resonance imaging protocols to monitor changes in tumor blood volume over time within the image's individual voxels
Specific Lung Cancer Susceptibility Gene Identified
piggy submitted, created time 1 year 4 months (www.sciencedaily.com)
University of Cincinnati (UC) cancer cell biologists have identified a distinct gene linked to increased lung cancer susceptibility and development. They say this gene, RGS17, could contribute to a genetic predisposition for lung cancer.
Upon further investigation, the team has concluded that this gene could be used to identify high-risk patients who may benefit from earlier, more aggressive lung cancer screening.
Soy May Aid in Treating Canine Cancers
sea-maid submitted, created time 1 year 4 months (www.sciencedaily.com)
Researchers at North Carolina State University are looking to soy as a way to make traditional canine cancer therapy more effective and less stressful for the dog and less costly for the owners.
Common Virus Kills Cancer Stem Cells
sea-maid submitted, created time 1 year 4 months (www.sciencedaily.com)
Dalhousie Medical School cancer researcher Dr. Patrick Lee has proven that a common virus can infect and kill breast cancer stem cells. This breakthrough finding is published in the current issue of Molecular Therapy, the journal of the American Society of Gene Therapy.
Chemical Compound May Stop Deadly Brain Tumors
piggy submitted, created time 1 year 4 months (www.sciencedaily.com)
Researchers at the University of North Carolina at Chapel Hill School of Medicine have identified a compound that could be modified to treat one of the most deadly types of cancer, and they have discovered how a particular gene mutation contributes to tumor growth.
The findings and potential treatment apply to a type of brain tumor called secondary glioblastoma multiforme (GBM). GBMs are part of a larger group of brain tumors called malignant gliomas, which is the type of cancer Senator Edward Kennedy suffers from.
Cutting off cancer's supply lines
sea-maid submitted, created time 1 year 4 months (www.nature.com)
Targeting the blood vessels that feed tumors may not be the silver bullet that oncologists have believed it to be, but refinements to the strategy may suggest further ways to treat the disease, Erika Check Hayden reports.
In some situations, angiogenesis inhibitors, drugs that choke off a tumor's blood supply, may speed up cancer's spread under some conditions and slow it down under others. Most blood vessels caused by cancer are "leaky and chaotic," as Nature puts it
Experimental Prostate Cancer Drug Shows Promise
sea-maid submitted, created time 1 year 4 months (www.time.com)
An experimental drug for advanced prostate cancer has shown preliminary success in Phase 1 and 2 clinical trials, shrinking cancer tumors in the lab and reducing signs of the disease in patients with drug-resistant cancer, according to a report published in the April 10 issue of the journal Science.
Breakthrough model for human cancer may improve development of cancer drugs
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
AVEO Pharmaceuticals, Inc., a biopharmaceutical company leveraging breakthrough discoveries in cancer biology to discover, develop and commercialize targeted oncology therapies, today announced findings from its novel human-in-mouse (HIM) cancer model system, in which AVEO successfully created invasive human tumors from primary human breast tissue. These tumors are placed in test mice, where they develop over time, mimicking the progress and responses of human tumors. The findings were published this week in the early edition of the Proceedings of the National Academy of Sciences.
piggy submitted, created time 1 year 4 months (www.sciencedaily.com)
Liver damage can be triggered by various insults, including hepatitis infection or alcohol-induced cirrhosis. In severe cases, this damage can lead to cancer. A new study by researchers at the National Institutes of Health and Osaka University reveals how one protein helps decide the fate of damaged livers in mice.
Liver cells rely on signals triggered by growth hormone to survive and multiply—functions that go haywire in cancer. Normally, growth hormone works by activating a signaling network inside liver cells that includes a protein called STAT5
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