Articles with the keyword: 
Mayo Clinic researchers discover and manipulate molecular interplay that moves cancer cells
piggy submitted, created time 1 year 5 months (www.eurekalert.org)
Based on studies into the mechanisms that allow invasive tumor cells to move, researchers at the Mayo Clinic campus in Florida have a new understanding about how to stop cancer from spreading. The act of cancer spreading from one part of the body to another (particularly the bloodstream), known as metastasis, is the process that most often leads to death from the disease.
In the March 29 online issue of Nature Cell Biology, researchers say that a molecule known as protein kinase D1 (PKD1) is key to the ability of a tumor cell to "remodel" its structure, enabling it to migrate and invade 
A sticky business -- how cancer cells become more gloopy as they die
piggy submitted, created time 1 year 5 months (www.eurekalert.org)
The viscosity, or gloopiness, of different parts of cancer cells increases dramatically when they are blasted with light-activated cancer drugs, according to new images that provide fundamental insights into how cancer cells die, published in Nature Chemistry today (15 March).
The images reveal the physical changes that occur inside cancer cells whilst they are dying as a result of photodynamic therapy (PDT). This cancer treatment uses light to activate a drug that creates a short-lived and toxic type of oxygen, called singlet oxygen, which kills cancerous cells
Decoy molecules drive cancer cells to suicide
sea-maid submitted, created time 1 year 6 months (news.yahoo.com)
French specialists on Sunday unveiled a new weapon against cancer -- a molecular decoy that mimics DNA damage and prompts cancerous cells to kill themselves.
Both chemotherapy and radiation therapy inflict damage on cancer cells in the hopes of triggering apoptosis, or programmed cell death. However, it doesn't always work and can also do a number on surrounding, healthy, tissues
How Cancer Cells Survive a Chemotherapy Drug
piggy submitted, created time 1 year 7 months (wis-wander.weizmann.ac.il)
What separates the few cancer cells that survive chemotherapy--leaving the door open to recurrence-–from those that don’t? Weizmann Institute scientists developed an original method for imaging and analyzing many thousands of living cells to reveal exactly how a chemotherapy drug affects each one.
For research student Ariel Cohen, together with Naama Geva-Zatorsky and Eran Eden in the lab of Prof. Uri Alon of the Institute’s Molecular Cell Biology Department, the question posed an interesting challenge
Potentially a New Way to Kill Cancer Cells
sea-maid submitted, created time 1 year 7 months (www.sciencedaily.com)
Scientists at Albert Einstein College of Medicine of Yeshiva University have identified a small intracellular protein that helps cells commit suicide. The finding could lead to drugs for combating cancer and other diseases characterized by overproduction of cells.
New Protein Function Discovered: Sheds Light on Intricate Mechanics of Cell Division
piggy submitted, created time 1 year 7 months (www.sciencedaily.com)
A group of Dartmouth researchers has found a new function for one of the proteins involved with chromosome segregation during cell division. Their finding adds to the growing knowledge about the fundamental workings of cells, and contributes to understanding how cell function can go wrong, as it does with cancerous cells.
The researchers studied a protein called NOD, distantly related to the motor proteins that power diverse cellular activities, including intracellular transport, signaling, and cell division
U-M researchers discover new genes that fuse in cancer
piggy submitted, created time 1 year 7 months (www.eurekalert.org)
Using new technologies that make it easier to sequence the human genome, researchers at the University of Michigan Comprehensive Cancer Center have identified a series of genes that become fused when their chromosomes trade places with each other. These recurrent gene fusions are thought to be the driving mechanism that causes certain cancers to develop.
The gene fusions discovered could potentially serve as a marker one day for diagnosing cancer or as a target for future drug development
Scientists can now differentiate between healthy cells and cancer cells
piggy submitted, created time 1 year 8 months (www.eurekalert.org)
One of the current handicaps of cancer treatments is the difficulty of aiming these treatments at destroying malignant cells without killing healthy cells in the process. But a new study by McMaster University researchers has provided insight into how scientists might develop therapies and drugs that more carefully target cancer, while sparing normal healthy cells
Mick Bhatia, scientific director of the McMaster Stem Cell and Cancer Research Institute in the Michael G
Dormant cancer cells rely on cellular self-cannibalization to survive
piggy submitted, created time 1 year 8 months (www.eurekalert.org)
A single tumor-suppressing gene is a key to understanding, and perhaps killing, dormant ovarian cancer cells that persist after initial treatment only to reawaken years later, researchers at the University of Texas M. D. Anderson Cancer Center report in the December Journal of Clinical Investigation.
The team found that expression of a gene called ARHI acts as a switch for autophagy, or self-cannibalization, in ovarian cancer cells. Often a mechanism for cancer cell death, in this case "self-eating" acts as a survival mechanism for dormant cancer cells
New Anti-cancer Components of Extra-virgin Olive Oil Revealed
piggy submitted, created time 1 year 8 months (www.sciencedaily.com)
Good quality extra-virgin olive oil contains health-relevant chemicals, called "phytochemicals, that can trigger cancer cell death. New research sheds more light on the suspected association between olive oil-rich Mediterranean diets and reductions in breast cancer risk.
Javier Menendez from the Catalan Institute of Oncology and Antonio Segura-Carretero from the University of Granada in Spain led a team of researchers who set out to investigate which parts of olive oil were most active against cancer
Low Levels of Two Enzymes in Ovarian Cancer Cells Shorten Survival
sea-maid submitted, created time 1 year 8 months (www.washingtonpost.com)
Women with ovarian cancer who had low levels of either of two enzymes associated with their tumors tended to die much sooner than women who had higher levels of one of the two enzymes, new research shows.
Researchers identify new anti-tumor gene
piggy submitted, created time 1 year 8 months (www.eurekalert.org)
Researchers from Virginia Commonwealth University have identified a new anti-tumor gene called SARI that can interact with and suppress a key protein that is overexpressed in ninety percent of human cancers. The discovery could one day lead to an effective gene therapy for cancer.
According to Paul B. Fisher, M.Ph., Ph.D
Lethal Lint Brush Captures and Kills Cancer Cells in the Bloodstream
piggy submitted, created time 1 year 8 months (www.sciencedaily.com)
In a new tactic in the fight against cancer, Cornell researcher Michael King has developed what he calls a lethal "lint brush" for the blood--a tiny, implantable device that captures and kills cancer cells in the bloodstream before they spread through the body.
The strategy, which takes advantage of the body's natural mechanism for fighting infection, could lead to new treatments for a variety of cancers, said King, who is an associate professor of biomedical engineering
Single cancer cell "poses danger"
sea-maid submitted, created time 1 year 9 months (news.bbc.co.uk)
Cancer researchers may have underestimated the power of some cancers to spread and cause new tumors, say U.S. researchers.
Scientists turbo-charge immune cells to fight cancer
piggy submitted, created time 1 year 10 months (news.yahoo.com)
Scientists in the United States have created super-charged immune cells that helped beat back cancer tumors in half of a small group of patients tested, according to a study released Sunday.
Adding an artificial receptor to T-lymphocyte immune cells boosted their ability to fight a deadly form of cancer called neuroblastoma, the researchers reported.
Neuroblastoma attacks the nervous system. While fairly rare, it accounts for seven percent of all childhood cancers, and fifteen percent of non-adult cancer deaths
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