Articles with the keyword: 


Industry shifts focus to immunology and cancer
sea-maid submitted, created time 1 week 4 days (www.nature.com)
Economic factors, including competition from generic drugs, is hitting even the big pharmaceutical companies hard, reports Nature. In 2010, Pfizer's Lipitor enters the public domain. For these reasons, the larger companies are narrowing the focus of their research, hitting fewer diseases. They're also working on fewer primary care drugs and more drugs that would be prescribed by specialists, such as cancer drugs.
"When Wyeth Pharmaceuticals announced last week that it would cut some of its research and development (R&D) programs in women's health, the decision seemed counterintuitive 


Novel anti-cancer mechanism found in long-lived rodents
sea-maid submitted, created time 2 months 1 day (esciencenews.com)
Biologists at the University of Rochester have found that small-bodied rodents with long lifespans have evolved a previously unknown anti-cancer mechanism that appears to be different from any anticancer mechanisms employed by humans or other large mammals. The findings are published in today's issue of Aging Cell. Understanding this mechanism may help prevent cancer in humans because many human cancers originate from stem cells and similar mechanisms may regulate stem cell division. 


Major Breakthrough in Cancer Research
jerry submitted, created time 2 months 1 week (www.efluxmedia.com)
By Alice Carver Scientists with the Johns Hopkins Kimmel Cancer Center at the Johns Hopkins University have managed to draw a map of the genetic mutations involved in two of the most aggressive cancers: glioblastoma, the most common form of brain. 


Researchers unveil vital key to cancer
sea-maid submitted, created time 3 months 2 weeks (www.manchester.ac.uk)
University of Manchester scientists have uncovered the 3D structure of Mps1 – a protein that regulates the number of chromosomes during cell division and thus has an essential role in the prevention of cancer – which will lead to the design of safer and more effective therapies. 


Pregnancy may help protect against bladder cancer in mice
kavin submitted, created time 4 months 3 weeks (esciencenews.com)
Pregnancy seems to confer some protection against bladder cancer in mice, scientists have found. Female mice that had never become pregnant had approximately 15 times as much cancer in their bladders as their counterparts that had become pregnant, according to new findings by investigators at the University of Rochester Medical Center. Their work appears online as a rapid communication in the journal Urology 
jane2007 submitted, created time 11 months 2 weeks (www.nature.com)
In 1981, Nature published a review about the possible link between high levels of dietary β-carotene and reduced rates of cancer.
In 1994, the results of those trials were in: β-carotene supplements, given together with vitamin E, did not protect against lung cancer as epidemiological studies had suggested they might. Instead, the supplements may actually have raised risk of developing the disease for male smokers. 


AICR Survey Uncovers Distorted Perceptions About What Causes Cancer
wugongliang submitted, created time 1 year 2 weeks (www.medicalnewstoday.com)
The most recent biennial survey commissioned by the American Institute for Cancer Research (AICR) shows that Americans rate cancer their number one health concern, believe it to be impossible to prevent, and continue to blame the disease on factors they cannot control. 


Report Reveals Convincing Links Between Growth Pattern, Cancer
wugongliang submitted, created time 1 year 2 weeks (www.medicalnewstoday.com)
The most comprehensive report on cancer prevention ever published shows that how the body grows is closely linked to one's cancer risk. The landmark American Institute for Cancer Research (AICR) report concluded that events that take place early in life greatly influence a person's cancer risk later on. 


New Cancer Treatments May Improve Survival Rates
saury submitted, created time 1 year 2 months (www.sciencedaily.com)
Doctors at St. Jude Children's Research Hospital today announced new brain tumor research protocols they hope will improve survival rates and reduce side effects of radiation therapy among pediatric cancer patients. 


Cells 'react' to GSM signals claims research
wugongliang submitted, created time 1 year 2 months (www.theregister.co.uk)
New research claims that cells can react to a GSM-like signal in as little as ten minutes - though if whether this could causes cancer remains open to interpretation. 


Heavy pesticide exposure linked to brain cancer
Reviver submitted, created time 1 year 5 months (www.reutershealth.com)
In a study of nearly 700 adults with or without brain tumors, French researchers found that agricultural workers with the highest level of exposure to pesticides were twice as likely to be diagnosed with brain cancer as those with no occupational pesticide exposure.There was also evidence that people who treated their house plants with pesticides had an elevated brain cancer risk. However, the researchers caution that this has not been seen in previous studies, and more research is needed to confirm whether the connection is real. 


Reviver submitted, created time 1 year 5 months (www.pnas.org)
"The humanized monoclonal antibody HzKR127 recognizes the preS1 domain of the human hepatitis B virus surface proteins with a broadly neutralizing activity in vivo. Researchers present the crystal structures of HzKR127 Fab and its complex with a major epitope peptide. In the complex structure, the bound peptide forms a type IV beta-turn followed by 310 helical turn, the looped-out conformation of which provides a structural basis for broad neutralization. Upon peptide binding, the antibody undergoes a dramatic complementarity determining region H3 lid opening 
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