Articles with the keyword: 
Cancer stem cells in solid tumors: accumulating evidence and unresolved questions
sea-maid submitted, created time 1 month 2 days (www.nature.com)
Solid tumors are an enormous cancer burden and a major therapeutic challenge. The cancer stem cell (CSC) hypothesis provides an attractive cellular mechanism to account for the therapeutic refractoriness and dormant behavior exhibited by many of these tumors. There is increasing evidence that diverse solid tumors are hierarchically organized and sustained by a distinct subpopulation of CSCs. Direct evidence for the CSC hypothesis has recently emerged from mouse models of epithelial tumorigenesis, although alternative models of heterogeneity also seem to apply 
Molecular Biologists Devise Strategy to Starve Brain Tumors
sea-maid submitted, created time 2 months 6 days (www.sciencedaily.com)
Brain tumor researchers have found that brain tumors arise from cancer stem cells living within tiny protective areas formed by blood vessels in the brain. Killing those cells is a promising strategy to eliminate tumors and prevents them from re-growing. The researchers have found that drugs that block new blood vessel formation can destroy the protected areas and stop cancer from developing.
DNA "Tattoos" Link Adult, Daughter Stem Cells in Planarians
sea-maid submitted, created time 2 months 6 days (www.sciencedaily.com)
The title of this article is poetic, but it could stand to be better organized. The authors refer to a certain method of DNA identification as a "tattoo," but don't immediately say what it is. One has to dig through the repetitive and error-strewn paragraphs before one finds this:
"the researchers devised methods to detect specific differences in gene expression in the BrdU-labeled cells. The researchers identified 259 genes associated with the stem cells and their daughters
Herceptin Targets Breast Cancer Stem Cells
kavin submitted, created time 4 months 1 week (www.sciencedaily.com)
A gene that is overexpressed in twenty percent of breast cancers increases the number of cancer stem cells, the cells that fuel a tumor’s growth and spread, according to a new study from the University of Michigan Comprehensive Cancer Center.
The gene, HER2, causes cancer stem cells to multiply and spread, explaining why HER2 has been linked to a more aggressive type of breast cancer and to metastatic disease, in which the cancer has spread beyond the breast, the researchers say
Twins, one with leukemia, illustrate cancer stem cell hypothesis
Darkfrog submitted, created time 10 months 3 days (www.nature.com)
Cancer stem cell hypothesis is the idea that some cancers, including leukemia, are caused by a small number of cancer stem cells. Even if the majority of the tumor is removed of zapped with chemo, the cancer will recur unless the cancer stem cells are dispatched.
The twin girls in this study are fraternal, not identical, and one of them has leukemia and the other does not. However, a group of cells in the healthy girl, Isabella, seemed to match the ill girl, Olivia, implying that they were transferred to her while the two of them were developing. Some of these cells were removed
The New Anticancer Weapon: Fetal Cells
Sue Wu submitted, created time 10 months 2 weeks (discovermagazine.com)
Having a child changes a woman's life in the biggest ways possible. It also seems to have the potential to change the mother in a tiny but very important way.
Loss of β-Catenin Impairs the Renewal of Normal and CML Stem Cells In Vivo
small melon submitted, created time 11 months 1 week (www.cancercell.org)
"A key characteristic of stem cells and cancer cells is their ability to self-renew. To test if Wnt signaling can regulate the self-renewal of both stem cells and cancer cells in the hematopoietic system, they developed mice that lack β-catenin in their hematopoietic cells. Here we show that β-catenin-deficient mice can form HSCs, but that these cells are deficient in long-term growth and maintenance
Fat In Stomach Can Turn Vitamin C Into A Cancer Trigger
june submitted, created time 1 year 2 months (www.medicalnewstoday.com)
Although vitamin C is known correctly for its cancer preventing qualities, fat in your stomach can alter it so that it forms certain cancer causing chemicals, according to a report published in the journal Gut.
Cancer Stem Cells Similar To Normal Stem Cells Can Thwart Anti-cancer Agents
Luneetty submitted, created time 1 year 5 months (www.sciencedaily.com)
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual metastasis.
\ 1
\ 
abuse@discover8.com
angelfish
jane2007
DanyC
addict
This antibody is rabbit serum against the E. coli derived re ...
www.genscript.com
PyBOP
amino acid : PyBOP
www.genscript.com
Urocortin III, human
Urocortin III (human) is a highly selective ligand for the C ...
www.genscript.com
U87MG
Human glioblastoma; 250 ug/250 ul.
www.genscript.com