Apoptosis: Killing neutrophils the cathepsin way

davidd submitted, created time 8 months 1 week (www.signaling-gateway.org)

Cathepsin D directly cleaves and activates caspase-8 at the beginning of a pro-apoptotic pathway in neutrophils, showing how apoptosis can be activated in the absence of death-receptor ligation.

2 comments | Blog It | Email It | Keywords: cell biology cell signaling neutrophils cell death cathepsin D caspase-8 apoptosis