Articles with the keyword: 
Study suggests some breast cancer patients facing radiation after a mastectomy may be over-treated
sea-maid submitted, created time 2 weeks 1 day (esciencenews.com)
A new study suggests standard radiation therapy for some breast cancer patients may not be medically required and may, therefore, be causing unnecessary serious side effects such as lymphedema and pulmonary problems. The research conducted at Fox Chase Cancer Center involved women who got a mastectomy, but whose lymph nodes were negative. "When a woman has a tumor greater than five centimeters and negative lymph nodes, a mastectomy followed by radiation is recommended," said Penny Anderson, M.D., attending physician in the radiation oncology department at Fox Chase 
Blocking enzyme could help in rare blood cancer
jerry submitted, created time 2 weeks 3 days (www.reuters.com)
An enzyme that fights some kinds of cancers may foster the growth of a rare type of leukemia that affects babies, U.S. researchers said on Wednesday in a finding that may lead to new drugs for the hard-to-treat disease. There is also talk of applications in Alzheimer's and diabetes.
The enzyme is called glycogen synthase kinase, or GSK3, and blocking it might be an effective way to treat this type of leukemia--for which chemotherapy is characteristically ineffective. Existing drugs used for bipolar disease seem to do a shaky but effective job.
Taxanes May Increase Risk for Significant Psychological Symptoms
kavin submitted, created time 1 month 5 days (www.medscape.com)
Taxane-based chemotherapies are increasingly used for the adjuvant treatment of early and locally advanced breast cancer, but new research suggests that they confer a risk for significant psychologic symptoms. According to a study published in the August 1 issue of Cancer, patients who received taxane-based therapy had significantly worse emotional distress and slower psychologic recovery than those receiving a similar regimen without taxanes.
The researchers also observed high rates of probable clinical depression among patients who received taxane therapy
Patient, Heal Thyself: Body's Own Immune Cells Whack Late-Stage Tumor
sea-maid submitted, created time 1 month 1 week (www.sciam.com)
In what could be a breakthrough in cancer therapy, researchers report in The New England Journal of Medicine today that they succeeded in bolstering a patient's immune system enough to wipe out late-stage malignant tumors on its own. The scientists say the successful experiment could pave the way for new treatments of advanced cancer that spare patients the side effects of chemotherapy, which kills healthy as well as malignant cells.....
Experimental chemotherapy regimen shows promise in treating advanced lung cancer
sea-maid submitted, created time 1 month 3 weeks (www.eurekalert.org)
A combination of chemotherapy agents that have been tested in other tumor types appears to be a promising alternative to standard treatment for advanced nonsmall cell lung cancer, according to a report in the Aug. 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.
sea-maid submitted, created time 2 months 7 hours (www.manchester.ac.uk)
University of Manchester researchers are investigating exactly how chemotherapy drugs kill cancerous tumors in a bid to reduce side effects and test the effectiveness of safer new agents.
Genetically engineered tobacco plants used to grow anti-lymphoma vaccine
Darkfrog submitted, created time 2 months 1 week (www.sciam.com)
Reports in the Proceedings of the National Academy of Sciences report that an experimental vaccines has triggered the immune systems of eleven (out of sixteen) patients to attack their tumors. The patients are afflicted with what is called follicular B-cell lymphoma. Dangerous side effects? None.
The interesting part? The vaccine was grown courtesy of some genetically engineered tobacco plants.
Of course, all of the patients were also receiving chemotherapy at the time, so it may be difficult to tell which results may be attributed to the vaccine itself
Mutation Spells Bad News for Breast Cancer Patients
sea-maid submitted, created time 4 months 6 days (sciencenow.sciencemag.org)
Breast cancer patients with a mutation in both copies of the NQO1 gene have a 20% lower survival rate five years after treatment than do patients without the mutation, according to a new study of more than 2000 Finnish women.
Starving before chemotherapy could save more lives
sumsung submitted, created time 6 months 6 days (www.newscientist.com)
Chemotherapy would have fewer side effects and save more lives if patients fasted for two days before receiving treatment, suggest tests in animals. Mice injected with cancerous cells and then given chemotherapy died after around 60 days. But animals that were starved for 48 hours prior to treatment typically lived 10-20 days longer, says Valter Longo of the University of Southern California in Davis, US. The longest-lived of the 16 mice that fasted did not die until around 14 weeks after being injected.
Hope May Be Useless Against Cancer
Sue Wu submitted, created time 7 months 3 weeks (discovermagazine.com)
New study finds that being happy won't help you live longer.
High expression of DNA repair pathways is associated with metastasis in melanoma patients
davidd submitted, created time 8 months 1 week (www.nature.com)
They find high expression of DNA repair pathways is associated with metastasis in melanoma patients. This overexpression of repair genes explains nicely the extraordinary resistance of metastatic melanoma to chemo- and radio-therapy. Their results may open a new avenue for the discovery of drugs active on human metastatic melanoma.
Hormone Could Ease Painful Lymphedema
sumsung submitted, created time 9 months 2 weeks (health.allrefer.com)
A hormone called adrenomedullin may prove an effective drug target for treating lymphedema, a painful swelling of the limbs that can follow breast cancer or other cancer treatment
Nanoparticles Enable Surgical Strikes against Cancer
jane2007 submitted, created time 10 months 1 week (www.sciam.com)
In a bid to progress beyond the shotgun approach to fighting cancer—blasting malignant cells with toxic chemicals or radiation, which kills surrounding healthy cells in the process—researchers at the Harvard-MIT Division of Health Sciences and Technology (HST) are using nanotechnology to develop seek-and-destroy models to zero in on and dismantle tumors without damaging nearby normal tissue.
Good News:Transplants Without Tears
Eric wu submitted, created time 10 months 1 week (sciencenow.sciencemag.org)
A new treatment might allow patients to avoid some of the grueling side effects of bone marrow transplants. Researchers reported in the 23 November issue of Science that they can use a specific type of antibody to clear away old marrow stem cells in mice, allowing fresh ones to take their place. The discovery could allow patients to receive bone marrow without undergoing chemotherapy and other toxic procedures.
Quantitative PET imaging finds early determination of effectiveness of cancer treatment
richard submitted, created time 11 months 1 week (interactive.snm.org)
With positron emission tomography imaging, seeing is believing: evaluating a patient's response to chemotherapy for non-Hodgkin lymphoma typically involves visual interpretation of scans of cancer tumors. Researchers have found that measuring a quantitative index -- one that reflects the reduction of metabolic activity after chemotherapy first begins -- adds accurate information about patients' responses to first-line chemotherapy, according to a study in the October issue of the Journal of Nuclear Medicine.
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