Articles with the keyword: 
House committee widens probe of Vytorin safety
jerry submitted, created time 1 month 1 day (www.iht.com)
A House committee investigating the safety and effectiveness of the popular cholesterol drug Vytorin and one of its components is turning up the heat on the drug's makers. 
Prostate cancer risk increased in obese men who use statin drugs
kavin submitted, created time 1 month 5 days (www.reuters.com)
Use of cholesterol-lowering statin drugs, especially long-term use, appears to raise the risk of prostate cancer among obese men, according to findings of a new study.
"Given the epidemic of obesity in the U.S. and the frequent use of statins, the positive association we observed raises substantial concern as to the safety of these widely prescribed agents," Dr. Janet L. Stanford of the Fred Hutchinson Cancer Research Center in Seattle and colleagues wrote in the American Journal of Epidemiology
Sudden hearing loss a harbinger of stroke
kavin submitted, created time 3 months 5 days (mobile.reuters.com)
NEW YORK (Reuters Health) - A sudden loss of hearing can be an early warning of impending stroke, according to results of a study released Thursday.
Dr. Herng-Ching Lin and colleagues at Taipei Medical University identified 1423 adult patients hospitalized in 1998 with a first episode of sudden hearing loss and matched each "case" patient to four "control" patients.
Patients in the hearing loss group were significantly more likely to have hypertension (high blood pressure), diabetes, and elevated cholesterol levels, the investigators note
Study finds good cholesterol may fight dementia
lily1984 submitted, created time 3 months 6 days (www.wsls.com)
Having low levels of HDL, or good cholesterol, does more than increase your risk for heart disease. It may also increase your risk for dementia.
Researchers at University College London analyzed blood samples and memory test results from over 35 hundred older adults. The study participants were followed for at least seven years. They found adults with low levels of HDL had an increased risk for dementia.
For example, participants with low HDL at age 55 had a 27% increased risk for the disease compared to those with high levels
Cholesterol-Lowering Drug May Be Ineffective
jane2007 submitted, created time 6 months 5 days (sciencenow.sciencemag.org)
A study found that combining an effective older cholesterol drug, simvastatin, with the drug ezetimibe was no better than simvastatin alone in preventing arterial plaques--one of the goals of cholesterol-lowering treatment. This has raised questions about whether this purportedly cholesterol-lowering drug may not benefit heart health.
MicroRNA Sets Stage for Human Therapies
sumsung submitted, created time 6 months 1 week (sciencenow.sciencemag.org)
Scientists have taken a big step toward developing therapies based on naturally occurring tiny RNA molecules called microRNAs. In the first successful experiment with primates, researchers have blocked microRNAs to lower cholesterol levels in monkeys. This achievement builds hope that the strategy could one day be used to attack human diseases. Safety concerns still linger, however.
Is Dr. Jarvik qualified to be a professional spokesman for Lipitor?
Darkfrog submitted, created time 7 months 4 weeks (www.nytimes.com)
Dr. Jarvik is famous for inventing a workable artificial heart, but he's not a cardiologist or even licensed to practice medicine. So why is he the face of choice for all those Lipitor ads? This article explores the propriety of these advertisements and lists inquiries into their ethics.
Dr. Jarvik isn' t just a celebrity face or a friendly testimonial. The use of his name implies some kind of expert endorsement, which he is not necessarily qualified to make
Extra calcium may raise health risks in older women
Sue Wu submitted, created time 8 months 3 weeks (www.reuters.com)
"Calcium supplements are commonly prescribed to postmenopausal women to maintain bone health, and some data suggest it might protect against vascular disease by lowering levels of LDL cholesterol, the so-called 'bad cholesterol', in the blood."
New Cholesterol Genes found are potentially attractive drug targets
DanyC submitted, created time 8 months 3 weeks (www.webmd.com)
Two of the newly identified genes only affect HDL cholesterol, one only affects LDL cholesterol, three only affect triglycerides, and one affects LDL cholesterol and triglycerides. it may be possible to tailor cholesterol and triglyceride treatments to patients
Genetic Polymorphism Tied to Sudden Death in Diabetics
kavin submitted, created time 9 months 3 weeks (www.medscape.com)
NEW YORK (Reuters Health) Dec 14 - The cholesterol ester transfer protein (CETP) TaqIB polymorphism is associated with the risk of sudden death in type 2 diabetic patients, according to French researchers.
Trial of Cholesterol Drug Gets House Scrutiny
jane2007 submitted, created time 9 months 3 weeks (www.nytimes.com)
A Congressional committee is investigating Merck and Schering-Plough for their handling of a critical clinical trial of Zetia, their blockbuster cholesterol-lowering drug.
Hope After Failure of New Cholesterol Drug
yangjane submitted, created time 11 months 1 day (www.nytimes.com)
Drugs to raise so-called good cholesterol may still have a future despite the widely publicized failure last year of an experimental cholesterol treatment from Pfizer, researchers said Monday at a heart conference here.
sumsung submitted, created time 1 year 1 week (www.pnas.org)
Coordinated regulation of bile acid biosynthesis, the predominant pathway for hepatic cholesterol catabolism, is mediated by few key nuclear receptors including the orphan receptors liver receptor homolog 1 (LRH-1), hepatocyte nuclear factor 4 (HNF4), small heterodimer partner (SHP), and the bile acid receptor FXR (farnesoid X receptor).
rprocyshyn submitted, created time 1 year 2 weeks (www.cma.ca)
This article suggests that serum lipids may play a role in clozapine's therapeutic acitivity. As such, it has implications in the treatment of dyslipidemias in clozapine treated patients.
Diet As Good As Drug For Lowering Cholesterol, Says Study
Reviver submitted, created time 1 year 3 weeks (www.sciencedaily.com)
Researchers at the University of Toronto and St. Michael's Hospital have shown that a vegetarian diet composed of specific plant foods can lower cholesterol as effectively as a drug treatment.
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