Study sees rise in U.S. colitis cases

DanyC submitted, created time 1 year 4 months (www.reutershealth.com)

U.S. researchers said on Monday, a common infection that causes diarrhea may be to blame for the nearly doubled incidence of a certain kind of colitis.

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Increased susceptibility to colitis and colorectal tumors in mice lacking core 3–derived O-glycans

julie submitted, created time 1 year 5 months (www.jem.org)

"Altered intestinal O-glycan expression has been observed in patients with ulcerative colitis and colorectal cancer, but the role of this alteration in the etiology of these diseases is unknown. O-glycans in mucin core proteins are the predominant components of the intestinal mucus, which comprises part of the intestinal mucosal barrier. Core 3–derived O-glycans, which are one of the major types of O-glycans, are primarily expressed in the colon

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