Articles with the keyword: 


Calcium May Only Protect Against Colorectal Cancer in Presence of Magnesium
sea-maid submitted, created time 3 days 15 hours (www.sciencedaily.com)
High magnesium intake has been associated with low risk of colorectal cancer. Americans have similar average magnesium intake as East Asian populations. If that were all that were involved, observers might expect both groups to have similar risk for colorectal cancer 


Health Highlights: The benefits of colon cancer screenings decline after seventy-five
jerry submitted, created time 1 month 2 weeks (www.washingtonpost.com)
Routine colon cancer tests should not be given to most people over age seventy-five, according to updated U.S. Preventive Services Task Force guidelines released Tuesday. After seventy-five, the benefits of finding and treating colon cancer decline. 


A little sun might fight cancer
sea-maid submitted, created time 4 months 1 week (www.newscientist.com)
Sunshine is regularly blamed for causing fatal skin cancers, but it may help save your life if you develop a different cancer. It seems that sunlight has an overall protective effect as it stimulates the body's production of vitamin D, which helps to combat internal cancers, including those of the colon and prostate.
"A little sun exposure is a little better for you than avoiding sunlight," says Richard Setlow of Brookhaven National Laboratory in Upton, New York, who co-led the new work 


Original CIN: reviewing roles for APC in chromosome instability
kavin submitted, created time 5 months 6 days (www.jcb.org)
You may have seen the bumper sticker "Eve was framed." Thousands of years of being blamed for original sin and still many wonder, where's the evidence? Today, the tumor suppressor adenomatous polyposis coli (APC) may have the same complaint about accusations of a different type of CIN, chromosome instability. A series of recent papers, including three in this journal, propose that loss of APC function plays an important role in the CIN seen in many colon cancer cells. However, a closer look reveals a complex story that raises more questions than answers. 
New Colon Cancer Screening Recommendations
DanyC submitted, created time 8 months 2 weeks (health.usnews.com)
Two tests are now being recommended: the virtual colonoscopy, which is an external CT scan that visualizes the colon without snaking a tube into it, and a stool test that detects mutated DNA shed from tumors. Those join the previously recommended screening tests, which include colonoscopy, sigmoidoscopy (in which a flexible tube is inserted in the rectum but not as far into the large bowel as with a colonoscopy), and different varieties of stool tests.
PS;
Colon cancer is one of the most common types of cancer in the U.S. It is the 2nd most frequently diagnosed disease in the U.S 


Genome update defines landscape of breast and colon cancers
james submitted, created time 1 year 1 month (www.eurekalert.org)
One year after completing the first large-scale report sequencing breast and colon cancer genes, Johns Hopkins Kimmel Cancer Center scientists have studied the vast majority of protein-coding genes which now suggest a landscape dominated by genes that each are mutated in relatively few cancers. 


jiangyun submitted, created time 1 year 2 months (carcin.oxfordjournals.org)
O-6-methylguanine-DNA methyltransferase (MGMT) repairs inappropriately methylated guanine residues in DNA. MGMT promoter methylation and gene silencing are common events in colorectal cancer, and may or may not coexist with the CpG island methylator phenotype (CIMP). 


jiangyun submitted, created time 1 year 2 months (carcin.oxfordjournals.org)
One of the liabilities of the ApcMin mouse as a model for colon cancer is its lack of a robust tumor response in the large bowel. In our protocol, we treated the ApcMin mouse with azoxymethane (AOM), a colon selective carcinogen. This protocol induced a 4-fold increase in the number of colon tumors. We utilized this protocol to investigate the possible mechanisms of inhibition of colorectal carcinogenesis by green tea (GT). 


jiangyun submitted, created time 1 year 2 months (carcin.oxfordjournals.org)
The quantitative nature of the present findings are inconsistent with the hypothesis that cancer cell lines respond differentially as compared to normal cells, and provide further evidence that PPARß/ ligands do not potentiate tumorigenesis. 


Choline may increase odds of polyps
kavin submitted, created time 1 year 3 months (www.reutershealth.com)
U.S. researchers' study found in red meat, poultry, eggs and milk -- may increase the risk of colon polyps, at least for women. choline is involved in similar processes as folate, a vitamin known to protect against genetic changes that can lead to cancer, researchers had thought choline might also have a protective effect. 


Japan study finds coffee may prevent colon cancer
DanyC submitted, created time 1 year 3 months (www.reutershealth.com)
According to a study by Japanese scientists, drinking three or more cups of coffee a day may cut the risk of colon cancer in women by half. 


Other highlights from the July 10 JNCI
bianjie submitted, created time 1 year 4 months (www.eurekalert.org)
Also in the July 10 JNCI are studies on a "nanobubble" drug delivery method, a gene that may promote chemotherapy drug resistance, and an association between vitamin D and reduced colon cancer risk. 


U-M, Israeli scientists report major advance in search for genes associated with colon cancer
bianjie submitted, created time 1 year 4 months (www.biologynews.net)
A 10-year study involving thousands of Israeli Jews and Arabs, led by researchers from American and Israeli institutions, has yielded important new information in the search for the genes that make a person more likely to develop colon cancer. 


Colon Cancer Proteins Show Promise For Blood Test
newsdigg submitted, created time 1 year 5 months (www.sciencedaily.com)
Searching for less invasive screening tests for cancer, Johns Hopkins scientists have discovered proteins present in blood that accurately identify colon cancer and precancerous polyps. Initial studies of the proteins, CCSA-3 and CCSA-4, suggest they could be used to develop a blood test to identify at-risk individuals. 


Can a Mediterranean diet prevent colon cancer?
sciencebaby submitted, created time 1 year 5 months (www.med.umich.edu)
U-M researchers to study how food choices affect cancer risk Study to compare Mediterranean diet with standard healthy diet 