FDA: Epilepsy drug may be risky for Asians

piggy submitted, created time 4 days 12 hours (www.fda.gov)

FDA is investigating new preliminary data regarding a potential increased risk of serious skin reactions including Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) from phenytoin therapy in Asian patients positive for a particular human leukocyte antigen (HLA) allele, HLA-B*1502. This allele occurs almost exclusively in patients with ancestry across broad areas of Asia, including Han Chinese, Filipinos, Malaysians, South Asian Indians, and Thais

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UV light fear over

Cosmetics companies mince words

Darkfrog submitted, created time 1 month 4 weeks (www.nytimes.com)

The next time you pick up a bottle of shampoo or moisturizer, take a look at the label. Does it claim to contain stem cells or growth hormone? For people who hang out on this website, the thought is probably, "Wait. Laboratories have a hard enough time growing their own stem cells. Who the #@%& is $#%!headed enough to put them in a 'rejuvenating night cream'?!"

It's hype. Of course it's hype

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Moisturizers Up Skin Cancer

kavin submitted, created time 3 months 2 weeks (www.medscape.com)

Four commonly used moisturizers promoted skin cancers in mouse studies.

Mice are not men. But the unexpected finding suggests that these — and perhaps other products — may not be as safe as they're thought to be.

The moisturizers tested in the study were Dermabase, Dermovan (a wholesale-only product discontinued in 2006), Eucerin Original Moisturizing Cream, and Vanicream.

In a mouse model of sun-related skin cancer, frequent application of each product resulted in more skin tumors and faster tumor growth, says study leader Allan H

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Intermittent Tacrolimus Ointment Therapy Helps Prevent Relapse of Stabilized Atopic Dermatitis

kavin submitted, created time 4 months 4 weeks (www.medscape.com)

NEW YORK (Reuters Health) Jun 23 - In patients with stabilized atopic dermatitis, intermittent therapy with tacrolimus ointment was associated with significantly more flare-free days and longer time to first relapse compared with vehicle alone, according to a report in the June issue of the Journal of the American Academy of Dermatology.

Tacrolimus is a topical calcineurin inhibitor (TCI) and is manufactured in ointment form under the brand name Protopic by Astellas Pharma US Inc., which supported this multicenter study by U.S. researchers

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Research suggests mechanism for acne drug’s link to depression

sally79 submitted, created time 11 months 1 week (www.scienceabode.com)

the article reveals interesting information on a acne drug causing depression.

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Skin cream tackles skin cancers in mice

Quality of life is severely compromised in adult patients with atopic dermatitis in Brazil, especially due to mental components

gh0706 submitted, created time 1 year 5 months (www.ncbi.nlm.nih.gov)

To measure the quality of life (QoL), either by a specific dermatology or generic self applied questionnaire, in Atopic dermatitis adult Brazilian patients, looking for selected affected groups. The researchers studied the quality of life of 75 Brazilian ambulatory adults with atopic dermatitis using two types of self-answered instruments: a quality of life generic questionnaire (SF-36) and a 10-item Dermatology Life Quality Index (DLQI) questionnaire. All patients had been treated for at least 6 months, and their disease status was determined by Eczema Area and Severity Index scores

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The Relation between Patterns of Vacation Sun Exposure and the Development of Acquired Melanocytic Nevi in German Children 6–7 Years of Age

badboy submitted, created time 1 year 7 months (aje.oxfordjournals.org)

"Sun exposure is the main environmental risk factor for the development of melanocytic nevi. Although the general association is not disputed, the interplay between intense intermittent and the cumulative amount of sun exposure in defining the promoting effect on melanocytic nevus development is an area of debate. "

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