Articles with the keyword:
9

Stable Blood Sugar Curbs Diabetes Complications

sea-maid submitted, created time 1 week 1 day (www.reuters.com)

In people with type 1 diabetes, adequate control of blood sugar over the long haul helps reduce the risk of diabetes-related eye and kidney disease, new data suggest.

The findings stem from a look at 1,441 type one diabetic patients followed for roughly nine years as part of the pivotal Diabetes Control and Complications Trial (DCCT)

10

Pure Insulin-Producing Cells Produced in Mice

piggy submitted, created time 1 week 3 days (www.sciencedaily.com)

Singapore researchers have developed an unlimited number of pure insulin-producing cells from mouse embryonic stem cells (ESCs).

These pure insulin-producing cells, which according to electron microscopy studies, have the same sub-cellular structures as the insulin-producing cells naturally found in the pancreas, were highly effective in treating diabetes in the mouse model.

The transplants of pure insulin-producing cells reduced the blood glucose levels of diabetic mice with high blood glucose levels

12

GlaxoSmithKline's customized "red wine" drug potent in mice

piggy submitted, created time 3 weeks 4 days (www.reuters.com)

LONDON (Reuters) - A drug in development that mimics a health-boosting compound found in red wine may be a powerful weapon in the fight against obesity and diabetes, researchers said on Tuesday.

A study of mice showed that the GlaxoSmithKline drug SRT1720 was about a thousand times more potent than resveratrol in activating an enzyme that helped the animals burn more energy and lower their insulin and glucose levels

8

Are Bacteria Foes of Diabetes?

sea-maid submitted, created time 2 months 1 week (sciencenow.sciencemag.org)

In mice, researchers uncover link between microbes and metabolic disease prevention. One team noticed that mice developed type 1 diabetes at different rates depending on whether and which strains of bacteria were floating around in their systems. The suggestion? Bacteria may mitigate certain forms of diabetes. We already knew that the darn things like sugar.

9

Scientists link chemical used in plastics to health problems

marry submitted, created time 2 months 1 week (www.startribune.com)

BPA was found to cause a higher risk of heart problems, diabetes and liver disease. The FDA repeated its stance that BPA is safe but is studying the issue.

5

Researchers link BPA exposure to health concerns

jerry submitted, created time 2 months 2 weeks (www.latimes.com)

In the first large-scale human study of the chemical, some found with bisphenol A in their urine had more than double the normal risk of heart disease and diabetes...

11

Gastric Bypass Surgery Less Helpful for Diabetics

jerry submitted, created time 2 months 2 weeks (www.time.com)

A new study suggests that the common weight-loss surgery leads to less weight loss in patients with diabetes.

9

Boosting good fat to burn off the bad

sea-maid submitted, created time 3 months 5 days (www.nature.com)

To most dieters, no fat is good fat. But in work published this week in Nature, an insight into the origin of a special class of calorie-burning fat cells could lead to new ways of boosting metabolism and combating obesity, researchers say.

This article outlines research suggesting that brown fat cells, which convert energy into heat but remain otherwise mysterious, may not arise from the same tissue as our garden-variety white fat cells

10

Gum Disease Signals Diabetes Risk

sea-maid submitted, created time 3 months 3 weeks (well.blogs.nytimes.com)

It’s long been known that oral health is an important indicator for the body’s overall health. Now new research suggests gum disease may predict whether you develop diabetes.

6

Three Kinds of Drugs That Can Kill Your Sex Drive

kavin submitted, created time 4 months 2 weeks (www.health.com)

Three Kinds of Drugs That Can Kill Your Sex Drive

If you're having sex drive issues, check your medicine cabinet. Several varieties of prescription medication can dampen desire.

Birth control:
Some hormonal birth control methods such as pills and patches can increase women's levels of sex-hormone-binding globulin (SHBG), which drops the amount of testosterone that's floating around freely in the bloodstream

7

Dietary Behaviors Predict Glycemic Control in Youth With Type 1 Diabetes

jerry submitted, created time 4 months 3 weeks (care.diabetesjournals.org)

OBJECTIVE—To investigate the association between dietary adherence and glycemic control among youth with type 1 diabetes.

RESEARCH DESIGN AND METHODS—We conducted a cross-sectional analysis of 119 youth aged 9–14 years (mean ± SD 12.1 ± 1.6 years) with diabetes duration 1 year (5.4 ± 3.1 years). Dietary adherence was assessed using the Diabetes Self-Management Profile diet domain. Higher score defined greater dietary adherence. Glycemic control was determined by A1C.

RESULTS—Dietary adherence score was inversely correlated with A1C (r = –0.36, P < 0.0001)

8

Intake of Fruit, Vegetables, and Fruit Juices and Risk of Diabetes in Women

jerry submitted, created time 4 months 3 weeks (care.diabetesjournals.org)

OBJECTIVE—The purpose of this study was to examine the association between fruit, vegetable, and fruit juice intake and development of type 2 diabetes.

RESEARCH DESIGN AND METHODS—A total of 71,346 female nurses aged 38–63 years who were free of cardiovascular disease, cancer, and diabetes in 1984 were followed for 18 years, and dietary information was collected using a semiquantitative food frequency questionnaire every 4 years. Diagnosis of diabetes was self-reported.

RESULTS—During follow-up, 4,529 cases of diabetes were documented, and the cumulative incidence of diabetes was 7.4%

10

They're calling it "biological alchemy": induced stem cells proliferate

sea-maid submitted, created time 4 months 3 weeks (www.newscientist.com)

CALL it biological alchemy: specialist pancreatic cells that secrete digestive enzymes have been converted directly into insulin-producing beta cells. Meanwhile, epithelial cells from the back of the eye have been coaxed into becoming a versatile, new type of stem cell.

Both advances, reported last week in Philadelphia, Pennsylvania, at the annual meeting of the International Society for Stem Cell Research (ISSCR), may take us closer to a "regenerative" approach to repairing damaged tissue

8

Cellular Islet Autoimmunity and Islet Cell Transplantation

jerry submitted, created time 4 months 4 weeks (www.plosone.org)

Islet cell transplantation can cure type 1 diabetes (T1D), but only a minority of recipients remains insulin–independent in the following years. They tested the hypothesis that allograft rejection and recurrent autoimmunity contribute to this progressive loss of islet allograft function.

Methodology/Principal Findings:
Twenty-one T1D patients received cultured islet cell grafts prepared from multiple donors and transplanted under anti-thymocyte globulin (ATG) induction and tacrolimus plus mycophenolate mofetil (MMF) maintenance immunosuppression

9

Potential Therapeutic Strategy for Type I Diabetes

jerry submitted, created time 4 months 4 weeks (diabetes.diabetesjournals.org)

Mesenchymal stem cells (MSCs) are pluripotent stromal cells that have the potential to give rise to cells of diverse lineages. Interestingly, MSCs can be found in virtually all postnatal tissues. The main criteria currently used to characterize and identify these cells are the capacity for self-renewal and differentiation into tissues of mesodermal origin, combined with a lack in expression of certain hematopoietic molecules. Because of their developmental plasticity, the notion of MSC-based therapeutic intervention has become an emerging strategy for the replacement of injured tissues

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