Articles with the keyword: 
Misreading of Damaged DNA May Spur Tumor Formation
sea-maid submitted, created time 1 week 1 day (www.sciencedaily.com)
The DNA in our cells is constantly under assault from oxygen, the sun's radiation and environmental stresses. Most of the time, our cells can repair the damage before it gets copied into a permanent mutation that could lead to cancer. 
Loulan Beauty upsets Chinese View of Colonization of Xinjiang
Darkfrog submitted, created time 1 week 4 days (www.nytimes.com)
In Xinjiang, a part of China that mainstream culture considers to be entirely Chinese, the discovery of over two hundred extremely well-preserved and marketly not Han Chinese mummies have called that assertion into question. Xinjiang borders Kazakh and Mongolia.
My take? Well DUH. Human beings migrate like crazy. Borders change. My ancestors moved from God-knows-where to Ireland, displacing the people who lived there earlier. Today we call their other descendants "Irish" and wouldn't think of calling them anything else
DNA: Too Much--or Too Little--Can Be a Bad Thing
piggy submitted, created time 2 weeks 1 day (sciencenow.sciencemag.org)
There's more variety to DNA than you might think: Deletions or additions of genetic material between individuals, called copy number variations (CNVs), are a common source of genetic diversity. Now, preliminary work reported here today at the American Society of Human Genetics meeting suggests that men who have more CNVs than average may be more likely to sire children with the eye cancer retinoblastoma
Biologists Discover Motor Protein That Rewinds DNA
piggy submitted, created time 4 weeks 1 day (www.sciencedaily.com)
ScienceDaily (Nov. 2, 2008) — Two biologists at the University of California, San Diego have discovered the first of a new class of cellular motor proteins that “rewind” sections of the double-stranded DNA molecule that become unwound, like the tangled ribbons from a cassette tape, in “bubbles” that prevent critical genes from being expressed.
“When your DNA gets stuck in the unwound position, your cells are in big trouble, and in humans, that ultimately leads to death” said Jim Kadonaga, a professor of biology at UCSD who headed the study
Genetics: Phoenicians leave their mark on the world ...again
Darkfrog submitted, created time 1 month 14 hours (www.nytimes.com)
If you look for "Phoenicia" on a map, you won't find it. The people, culture and language were dead when the Romans were still Roming all over the place. (As a matter of fact, these two events were directly related; darn legionnaires!) Still, you're heard of the Phoenicians before. Maybe you don't remember precisely when, but it's something that reminds you of stone and Greece and a sea that is for some reason wine-dark.
It could be because Phoenicia had a huge trading empire and a huge influence on the ancient Mediterranean
sea-maid submitted, created time 2 months 4 days (www.jcb.org)
Active genes can be sociable, snuggling up to one another. Brown et al. offer a new explanation for this clustering, suggesting that genes gather for the services of RNA splicing enzymes
A gene's location in the nucleus often reflects its activity. Hard-working genes tend to congregate in the interior of the nucleus, whereas their lazier counterparts hang out at the edge. Moreover, active genes on different chromosomes sometimes bunch up. How often active genes come together is uncertain
Gene regulation makes humans human
sea-maid submitted, created time 2 months 3 weeks (www.sciencenews.org)
The regulation of genes, rather than genes alone, may have been crucial to primate evolution. Nearly identical stretches of DNA in chimps and humans trigger different effects in the developing body, triggered by non-coding regions.
Woolly mammoths native to what's now the U.S., says study
Darkfrog submitted, created time 2 months 3 weeks (sciencenow.sciencemag.org)
Recent DNA tests of preserved DNA have allowed us to sort prehistoric mammoths into three groups: One subspecies lived in Eurasia, one in North America, and another ranged through both. For a long time, it was thought that mammoths originated in Eurasia because the fossils that have been found there are older. While this seems to be true, the studies also show that the subspecies that arose in North America crossed the Bering Strait and supplanted the other two a few hundred thousand years ago.
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Missing DNA Boosts Risk of Schizophrenia
sea-maid submitted, created time 3 months 4 weeks (sciencenow.sciencemag.org)
Two large studies of schizophrenia patients have yielded the most convincing evidence yet that the disease can be caused by mistakes in genes. The researchers linked a much higher risk for schizophrenia to three chromosomal regions that are missing chunks of DNA. Although only a tiny fraction of patients carried these particular glitches, similar errors may help explain other cases of the disease.
Once suspect protein found to promote DNA repair, prevent cancer
sea-maid submitted, created time 4 months 1 week (esciencenews.com)
An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of the National Academies of Science. The protein, HMGB1, was previously hypothesized to block DNA repair, senior author Karen Vasquez, Ph.D., associate professor in M. D. Anderson's Department of Carcinogenesis at the Science Park - Research Division in Smithville, Texas.
jerry submitted, created time 4 months 1 week (sciencenow.sciencemag.org)
When it comes to the extremely difficult task of sequencing caveman DNA, the third time may be the charm for David Caramelli. After two controversial attempts, the biological anthropologist at the University of Florence, Italy, and colleagues claim to have successfully sequenced mitochondrial DNA (mtDNA) from the fossils of a Cro-Magnon, a 28,000-year-old European ancestor of living humans. The mtDNA matches that of some modern Europeans but differs from that of Neandertals, shedding light on the fate of these ancient hominids
Lifetime lessons of DNA change
sea-maid submitted, created time 5 months 5 days (www.nature.com)
Study of how genome is chemically altered as we age could help us understand disease.
Life Cooked Up in Outer Space?
jerry submitted, created time 5 months 1 week (sciencenow.sciencemag.org)
The odds are improving that life exists beyond Earth. A European-U.S. team reports that a meteorite that formed billions of years ago and eventually crashed on our planet harbors two important components of RNA and DNA, the fundamental molecules of life. The findings could help explain how life got started on Earth, and they suggest that the ingredients for life have been liberally sprinkled throughout the solar system, if not the galaxy.
jerry submitted, created time 6 months 2 days (www.sciencedaily.com)
Researchers have determined the DNA sequence of a woman. She is also the first European whose DNA sequence has been determined...
sea-maid submitted, created time 6 months 1 week (www.jcb.org)
Earnshaw's group was hoping to crack a different question: how the cell's chromatin condenses during mitosis. In order to find the answer, they allowed researchers to create synchronized systems to study how protein-slicing enzymes such as the caspases orchestrate apoptosis.
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Schistosoma Japonicum glutathione S-transferase (GST) is a 2 ...
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LLC1
Mouse Lewis lung carcinoma; 250 ug/250 ul.
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