Articles with the keyword: 


sea-maid submitted, created time 1 week 5 days (www.nature.com)
Observers could be forgiven for thinking they had spotted a phoenix rising from the ashes of Advanced Cell Technology (ACT) earlier this week. The Los Angeles, California-based company, which is devoted to turning human embryonic stem cells into therapies, had been reported on the verge of extinction last month after it told the U.S. Securities and Exchange Commission that it would run out of money on 31 July 


First red blood cells grown in the lab
sea-maid submitted, created time 2 weeks 2 days (www.newscientist.com)
Blood donations may one day be a thing of the past thanks to the creation of the first functional red blood cells grown in the lab. The cells were grown from human embryonic stem cells (ESCs). 
Consent issues restrict stem-cell use and research
sea-maid submitted, created time 1 month 1 week (www.nature.com)
Some researchers in Stanford University are told that around one-quarter of the human embryonic stem-cell lines eligible for U.S. government funding are now off-limits because of ethical concerns. The university is concerned that some of the women who donated the embyros that were used to generate the line might not have been fully informed of how they would be used.
The consent forms that the women signed were retrieved and it was found that none of them met Standford's guidelines exactly and some of them were way off the mark 


Stem cell meeting 2008: complications for induced pluripotent stem cells
sea-maid submitted, created time 1 month 2 weeks (www.nature.com)
This year's meeting of the International Society for Stem Cell Research in Philadelphia, Pennsylvania, included a jam-packed session on the standards and methodologies of creating induced pluripotent stem cells. But although excitement around advances in reprogramming somatic cells shows no signs of abating, new ideas regarding the field are surfacing.
One announcement in particular may have consequences for induced pluripotent stem cells: It seems that ever reprogrammed cells can retain some echoes of their differentiated states, which researchers have nicknamed "cellular memory 


Embryonic stem cells answer questions about breast cancer
sea-maid submitted, created time 1 month 2 weeks (www.nature.com)
Mutations in the BRCA1 and BRCA2 genes dramatically increase a woman's risk of breast cancer, and some women consider genetic screening in the hopes of earlier detection and treatment. Commercial tests can detect common variants associated with risk, but many mutations are unclassified 


Harvesting stem cells at the four-cell stage can be easier and safer
Darkfrog submitted, created time 1 month 4 weeks (blog.wired.com)
Here is a Wired Science writeup of that article I posted yesterday. It's less detailed, but it's easier to read. Again, the top story is that researchers have found a new way to harvest stem cells from embryos without destroying them: taking a cell at the four-cell stage produces cell lines that don't need to be co-cultured. And we already know from fertility treatments that the remaining three cells can grow into healthy children. 


Stem cells: One more roadblock removed from the path to practical induced pluripotency
Darkfrog submitted, created time 2 months 4 days (blog.wired.com)
This team from the Whitehead Institute for Biological Research has moved induced pluripotent stem cells one step closer to maturity. Using a two-pronged approach, they used a virus to insert the genes into mouse cells, but employ a drug to switch them on and off. This makes hte cells less likely to turn cancerous. The process is written up in Nature Biotechnology. Unlike previous iPS techniques, this produces a culture of genetically identical cells, something that iPS to date had not yet been able to do 


sea-maid submitted, created time 2 months 1 week (www.nature.com)
In this study, the author provide new strategies which could lead to changes in the quality, quantity of induced pluripotent cells. 


Small molecules for stem cells
sea-maid submitted, created time 2 months 3 weeks (www.nature.com)
Embryonic stem cells are hard to grow, study and use. I Sheng Ding of the Scripps Research Institute in La Jolla, California, describes identifying small molecules that not only help improve techniques used to manipulate stem cells in culture but also answer questions about the cells' basic function. 


Stem cells improve myelination in shiverer mice
Darkfrog submitted, created time 3 months 2 days (www.nature.com)
Researchers have used human glial progenitor cells taken from fetal white matter to cure shiverer mice of thier shakes. Although the mice were still obviously ill, some of them lived much longer than their controls. The control mice were all dead by 130 days, but some of the injected mice lived for eighteen months. When they were dissected, researchers found a level of myelination that they refer to as "stunning." They also note that the logner the mice lived, the better they got 


Stem cell therapy clinical trial halted by the FDA
Darkfrog submitted, created time 3 months 2 weeks (www.nature.com)
The FDA has put the brakes on a clinical trial, mentioned on DiscoveR8 a few months ago: Geron company in California wants to inject the spines of spinal injury patients with oligodendroglial progenitor cells grown from embryonic stem cells.
At first I thought, "Good, a little caution never hurt anyone," but then I read that this trial has been in the works for four years. You know what? That four-year delay probably has hurt someone.
The FDA has NOT STATED ITS REASONS for the delay 


Beating heart tissue produced in laboratories
sea-maid submitted, created time 4 months 1 week (www.nature.com)
An international team of researchers has used stem cells to create heart tissue, complete with beat. By treating embryonic stem cells with growth factors, they coaxed them into becoming cardiovascular progenitor cells, which then developed into cardiomyocytes, vascular smooth muscle cells, and endothelial cells, which together form blood vessels. When injected into the hearts of mice with induced heart disease, they improve heart function.
What this discovery does not include is fibroblasts, the cells that form the framework of the heart. 


Embryonic stem cells coaxed into key heart cells
sumsung submitted, created time 4 months 1 week (www.sciam.com)
Scientists say they have coaxed human embryonic stem cells into becoming three of the major cell types in the human heart, and they improved cardiac function when transplanted into mice. The findings, published in the journal Nature on Wednesday, showed that scientists can efficiently make different kinds of human heart cells for use in basic and clinical research. The researchers said that in the short term, they could be used to test how heart cells respond to different drugs 


FDA to vet embryonic stem cells’ safety
jane2007 submitted, created time 4 months 4 weeks (www.nature.com)
Investors, biotech companies and other stem-cell stakeholders are meeting in Gaithersburg, Maryland, this week for FDA’s first public hearing on the safety of therapies that use human embryonic stem cells. 
Breakthrough!--Cloned cells treat Parkinson's in mice
Sue Wu submitted, created time 5 months 2 weeks (www.nature.com)
Researchers who used cloned embryonic stem cells to treat Parkinson's disease in mice said on Sunday they worked better than other cells. 