Articles with the keyword:
11

Scientists discover genetic variant tied to increased stroke risk

piggy submitted, created time 1 year 4 months (www.eurekalert.org)

Millions of people have a genetic variant linked to increased risk of ischemic stroke, reports an international research team including scientists at the University of Texas Health Science Center at Houston. The study was published online by the New England Journal of Medicine on April 15.

Ischemic stroke accounts for nearly ninety percent of all strokes and is caused by blockage of blood to the brain. More than 150,000 Americans succumb to stroke every year, making it the third leading cause of death. Survivors often experience permanent stoke-related disabilities.

11

Specific Lung Cancer Susceptibility Gene Identified

piggy submitted, created time 1 year 4 months (www.sciencedaily.com)

University of Cincinnati (UC) cancer cell biologists have identified a distinct gene linked to increased lung cancer susceptibility and development. They say this gene, RGS17, could contribute to a genetic predisposition for lung cancer.

Upon further investigation, the team has concluded that this gene could be used to identify high-risk patients who may benefit from earlier, more aggressive lung cancer screening.

13

Gene Linked to Deadly Disorder in Newborns Identified

piggy submitted, created time 1 year 4 months (www.sciencedaily.com)

After twelve years of searching, UCLA scientists have tracked down the first known gene mutation responsible for a heartbreaking disorder that kills newborn babies. Published in the April 1 online edition of the American Journal of Human Genetics, their findings will allow for earlier testing of embryos at risk for the disease.

Many things go awry in short-rib polydactyly syndrome. The fetus develops extra fingers and toes and its skeleton doesn't grow, resulting in stunted ribs that prevent the lungs from maturing in the womb

12

Magnetic Nanoparticles Navigate Therapeutic Genes Through the Body

sea-maid submitted, created time 1 year 5 months (www.sciencedaily.com)

Scientists of the national German metrology institute, the Physikalisch-Technische Bundesanstalt (PTB), have developed a highly sensitive means of measuring the efficiency of gene transfer in cases if cardiovascular diseases.

11

Abuse Leaves Its Mark on the Brain

piggy submitted, created time 1 year 6 months (sciencenow.sciencemag.org)

Child abuse doesn't just cause emotional problems; it also causes long-lasting changes the brain. A new study shows that in men who were abused as children, a gene involved in stress control is affected even decades later, following a pattern also seen in stressed baby rats.

Rat studies have revealed that maternal neglect alters the workings of the hypothalamic-pituitary-adrenal (HPA) axis, a system that secretes particular hormones in response to stress

11

Longevity Gene Common Among People Living to 100 Years Old and Beyond

piggy submitted, created time 1 year 7 months (www.sciencedaily.com)

A variation in the gene FOXO3A has a positive effect on the life expectancy of humans, and is found much more often in people living to 100 and beyond. Moreover, this appears to be true worldwide.

A research group in the Faculty of Medicine at the Christian-Albrechts-University in Kiel (CAU) has now confirmed this assumption by comparing DNA samples taken from 388 German centenarians with those from 731 younger people. The results of the study appear this week in the journal Proceedings of the National Academy of Sciences ("PNAS").

12

Single Gene Lets Bacteria Jump from Host to Host

piggy submitted, created time 1 year 7 months (www.sciencedaily.com)

All life — plants, animals, people — depends on peaceful coexistence with a swarm of microbial life that performs vital services from helping to convert food to energy to protection from disease.

Now, with the help of a squid that uses a luminescent bacterium to create a predator-fooling light organ and a fish that uses a different strain of the same species of bacteria like a flashlight to illuminate the dark nooks of the reefs where it lives, scientists have found that gaining a single gene is enough for the microbe to switch host animals.

The finding, reported this week (Feb

8

First Gene Discovered for Most Common Form of Epilepsy

piggy submitted, created time 1 year 7 months (www.sciencedaily.com)

An international team of researchers, led by investigators at Columbia University Medical Center, has uncovered the first gene linked to the most common type of epilepsy, called Rolandic epilepsy. One out of every five children with epilepsy is diagnosed with this form, which is associated with seizures starting in one part of the brain.

This finding is the first step in unlocking the causes of common childhood epilepsies and developing more effective treatments

9

Genetic Mutation Causes Familial Susceptibility for Degenerative Brain Disease

sea-maid submitted, created time 1 year 7 months (www.sciencedaily.com)

Mutation of a gene that helps proteins migrate in and out of the cell's genetic command center – the nucleus – puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE).

10

Gene Ups Risk for Those on Blood-Thinner Plavix

sea-maid submitted, created time 1 year 8 months (www.nlm.nih.gov)

A gene variation can make younger heart attack patients more prone to another heart attack, death or other heart problems if they receive the anti-clotting drug Plavix, a trio of new studies finds.

8

Researchers discover gene that helps control the production of stomach acid

sea-maid submitted, created time 1 year 10 months (www.eurekalert.org)

University of Cincinnati (UC) researchers have discovered a gene that helps control the secretion of acid in the stomach—information that could one day aid scientists in creating more efficient treatment options for conditions such as acid reflux or peptic ulcers

7

Yeast reveals sexual selection in action

sea-maid submitted, created time 1 year 10 months (www.nature.com)

The yeast microbe provides way to track evolution gene by gene.

Sexual selection is difficult to work with in complex species. Scientists dispute over whether sexually favored traits represent side effects of healthy immune systems or other desirable traits or whether these preferences arise arbitrarily. One of the reasons that this is so difficult to figure out is that the traits involve multiple genes.

7

Gene surveys identify schizophrenia triggers

sea-maid submitted, created time 2 years 1 month (www.nature.com)

Rare genetic changes associated with a heightened risk of schizophrenia have been revealed by two independent studies.

The surveys have identified sections of the human genome that, when deleted, can elevate the risk of developing schizophrenia by up to fifteen times compared with the general population.

6

"Junk" RNA may play a role in vertebrate evolution

sumsung submitted, created time 2 years 6 months (www.sciam.com)

Genetic material once dismissed as mere "junk" may in fact be responsible to the evolution of simple invertebrates into more complex organisms sporting backbones, according to a new study.

5

Drug addiction genes identified

sumsung submitted, created time 2 years 7 months (ca.reuters.com)

Scientists in China have identified about 400 genes that appear to make some people more easily addicted to drugs, opening the way for more effective therapies and addiction control.

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